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COL9A3

Official Full Name

collagen, type IX, alpha 3
Overview

This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3.
Synonyms

COL9A3; collagen, type IX, alpha 3; collagen alpha-3(IX) chain; collagen type IX proteoglycan; DJ885L7.4.1; EDM3; FLJ90759; IDD; MED; alpha 3 type IX collagen; collagen IX alpha-3 polypeptide; collagen type IXalpha 3; OTTHUMP00000031507; collagen IX, alpha-3 polypeptide;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

HEK293
HEK293T
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Flag
GST
His
His (Fc)
Avi
Myc
DDK
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	COL9A3-1665H	Recombinant Human COL9A3 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	COL9A3-7374HCL	Recombinant Human COL9A3 293 Cell Lysate	HEK293	N/A	Inquiry
Human	COL9A3-640H	Recombinant Human COL9A3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	COL9A3-1680H	Recombinant Human COL9A3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	COL9A3-2143HFL	Recombinant Full Length Human COL9A3 Protein, C-Flag-tagged	Mammalian cells	Flag	Inquiry
Human	COL9A3-640H-B	Recombinant Human COL9A3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Col9a3-920M	Recombinant Mouse Col9a3 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Chicken	COL9A3-6857C	Recombinant Chicken COL9A3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

COL9A3 involved in several pathways and played different roles in them. We selected most pathways COL9A3 participated on our site, such as Axon guidance, Collagen biosynthesis and modifying enzymes, Collagen degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL9A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Axon guidance	UNC5A;SPTBN2;EFNB1;EPHA8;WDR83;ROCK2;EPHA5;SRGAP1;ST8SIA2
Collagen biosynthesis and modifying enzymes	PCOLCE2;COL6A1;EMID2;LEPRE1;COL3A1;COL5A2;COL8A2;COL6A2;COL5A1
Collagen degradation	MGC174155;COL17A1;MMP20;COL9A1;ADAM9;ADAM10;MMP12;TLDC2;CTSB
Collagen formation	CD151;COL4A5;TLL1;LOXL1;PCOLCE;COL8A1A;COL9A3;MMP13;TLL2
Degradation of the extracellular matrix	CTSK;CMA1;ADAM15;CTSLL;ADAM8;ACAN;FURINB;BMP1A;COL19A1
Developmental Biology	CTNNA2;NTN1A;LAMTOR2;RGMA;SCN3A;LGI3;JAK3;COL9A1;EVL
ECM proteoglycans	VCANB;LRP4;MATN1;DMP1;ACAN;PTPRS;COL9A1;ASPN;COL9A3
Extracellular matrix organization	TIMP2B;ASPN;ADAMTS4;ADAM8A;PCOLCE;CMA1;COL17A1;LOC100514666;DAG1

COL9A3 has several biochemical functions, for example, extracellular matrix structural constituent conferring tensile strength. Some of the functions are cooperated with other proteins, some of the functions could acted by COL9A3 itself. We selected most functions COL9A3 had, and list some proteins which have the same functions with COL9A3. You can find most of the proteins on our site.

Function	Related Protein
extracellular matrix structural constituent conferring tensile strength	COL9A3;COL2A1;COL9A1

COL9A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL9A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL9A3.

EGFR