csf2rb
Share
  • Official Full Name
  • colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
  • Background
  • The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
  • Synonyms
  • CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimu
Cat.#:CSF2RB-1972HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CSF2RB Protein
+Inquiry
Cat.#:CSF2RB-3347HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF2RB Protein, MYC/DDK-tagged
+Inquiry
Cat.#:CSF2RB-186HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CSF2RB protein, His-tagged
+Inquiry
Cat.#:CSF2RB-2231HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF2RB, Fc tagged
+Inquiry
Cat.#:CSF2RB-29794THTag:Fc
Source (Host):Species:Human
Product nameRecombinant Human CSF2RB, Fc-tagged
+Inquiry
Cat.#:CSF2RB-3177HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF2RB, His tagged
+Inquiry
Cat.#:CSF2RB-7090HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSF2RB protein, His & GST-tagged
+Inquiry
Cat.#:CSF2RB-3964MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CSF2RB Protein
+Inquiry
Cat.#:Csf2rb-32RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Csf2rb, Fc tagged
+Inquiry
Cat.#:CSF2RB-6370ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CSF2RB
+Inquiry
Cat.#:CSF2RB-2235HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSF2RB cell lysate
+Inquiry
Cat.#:CSF2RB-1137RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CSF2RB cell lysate
+Inquiry

Involved Pathway

CSF2RB involved in several pathways and played different roles in them. We selected most pathways CSF2RB participated on our site, such as ARMS-mediated activation, Apoptosis, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF2RB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ARMS-mediated activation
NETO2; FGF10B; SPTB; FRS2; FGF18B; SPNA2; RASGRP4; CNKSR1; DUSP4; DUSP1
Apoptosis
PRKACAB; CRADD; PIK3CA; PRKACB; PLECA; BIRC2; CSF2RB; CASP3B; CASP8L1; BAD
Axon guidance
UNC5C; SEMA6B; SPNA1; CD24; CXCR4; PLXNA1; SEMA3G; CDK5; SLIT2; AP2A1
Cytokine Signaling in Immune system
UBE2V1; GBP1; TRIM29; TRIM31; FGFR1B; IRAK3; HBEGF; IFI35; ARIH1; IFIT10
Cytokine-cytokine receptor interaction
INHBA; IFNE; ACVR1B; TNFRSF1A; LEPA; TGFBR1B; IFNW1; THPO; NT5C3; BMPR2A
DAP12 interactions
PRKAR1AA; SIRPB1; DUSP10; PAQR3A; FGFR1B; JAK3; AHCYL1; SPTB; SIGLEC15; SPTBN2
DAP12 signaling
FGF10B; NEFLB; DUSP10; AGO1; WDR83; IL17RD; FGF8B; FRS3; PEBP1; SPRED2
Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
SFTPC; CSF2RB; SFTPB; CSF2RA

Protein Function

CSF2RB has several biochemical functions, for example, contributes_to interleukin-3 receptor activity, contributes_to interleukin-5 receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF2RB itself. We selected most functions CSF2RB had, and list some proteins which have the same functions with CSF2RB. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to interleukin-3 receptor activity
Related Protein CSF2RB
Function contributes_to interleukin-5 receptor activity
Related Protein CSF2RB
Function protein binding
Related Protein TBC1D19; PFKFB2; STAC3; ZBTB2; RASD1; PKP2; COPS5; CASP14; TTC25; AMDHD2
Function receptor activity
Related Protein TNFRSF11B; GRIA3A; MCC; VPREB1; CSF3R; CUL5; BTLA; TMEM123; CD5; VMN1R49

Interacting Protein

CSF2RB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF2RB here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF2RB.
JAK2; ITGB1; SHC1; PTPN11; CSF2; IL5; PTPN6