Active Recombinant Human CSF2RB protein, His-tagged

• Cat.No.: CSF2RB-3177H
• Product Overview: Recombinant Human CSF2RB protein(NP_000386.1)(Met1-Trp443), fused with His tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Met1-Trp443
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized human CD131 at 10 μg/ml (100 μl/well) can bind human Fc-GMCSF, The EC50 of human Fc-GMCSF is 250-500 ng/ml.
• Molecular Mass: The recombinant human CSF2RB consists of 438 amino acids and has a predicted molecular mass of 50 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CSF2RB is approximately 50-55 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 97 % as determined by SDS-PAGE
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Homo sapiens ]
• Official Symbol: CSF2RB
• Synonyms: CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); SMDP5; CDw131
• Gene ID: 1439
• mRNA Refseq: NM_000395
• Protein Refseq: NP_000386
• MIM: 138981
• UniProt ID: P32927