csnk2a1
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  • Official Full Name
  • casein kinase 2, alpha 1 polypeptide
  • Background
  • Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
  • Synonyms
  • CSNK2A1; casein kinase 2, alpha 1 polypeptide; casein kinase II subunit alpha; CK II alpha; protein kinase CK2; CK2 catalytic subunit alpha; casein kinase II alpha 1 subunit; CKII; CK2A1
Cat.#:CSNK2A1-2005HTag:GST
Source (Host):Insect CellsSpecies:Human
Product nameRecombinant Human CSNK2A1 Protein, GST-tagged
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Cat.#:CSNK2A1-2006HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CSNK2A1 Protein, GST-tagged
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Cat.#:CSNK2A1-3356HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CSNK2A1 Protein, MYC/DDK-tagged
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Cat.#:CSNK2A1-166HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CSNK2A1
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Cat.#:CSNK2A1-190HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSNK2A1 protein, His-tagged
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Cat.#:CSNK2A1-191HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CSNK2A1 protein, DDK-tagged
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Cat.#:CSNK2A1-199HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSNK2A1, His-tagged
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Cat.#:CSNK2A1-27173THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CSNK2A1
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Cat.#:CSNK2A1-28001THTag:
Source (Host):Species:Human
Product nameRecombinant Human CSNK2A1
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Cat.#:CSNK2A1-283HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CSNK2A1, GST-tagged, Active
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Cat.#:CSNK2A1-892HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSNK2A1, GST tagged
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Cat.#:CSNK2A1-478MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Csnk2a1, Gly & Pro tagged
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Cat.#:Csnk2a1-7401MTag:His/GST
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Csnk2a1, His & GST tagged
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Cat.#:CSNK2A1-1637RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CSNK2A1 Protein
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Cat.#:CSNK2A1-1062RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CSNK2A1 Protein, His-tagged
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Cat.#:CSNK2A1-1183CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CSNK2A1
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Cat.#:CSNK2A1-8849ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CSNK2A1
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Cat.#:CSNK2A1-21HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human casein kinase 2, alpha 1 polypeptide
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Cat.#:CSNK2A1-1208HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Casein Kinase 2, Alpha 1 Polypeptide, His-tagged
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Cat.#:CSNK2A1-634HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CSNK2A1 cell lysate
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Cat.#:CSNK2A1-001MCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse CSNK2A1 cell lysate
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Involved Pathway

CSNK2A1 involved in several pathways and played different roles in them. We selected most pathways CSNK2A1 participated on our site, such as Adherens junction, Alpha-synuclein signaling, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSNK2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adherens junction
INSRA; BAIAP2A; PTBP3; SMAD3A; RAC3A; LMO7; ACTB1; FARP2; ACTB2; INSRB
Alpha-synuclein signaling
BLK; TOR1A; PARK7; KLK6; CSNK2A1; STUB1; FKBP1A
Axon guidance
NRP1A; EPHA10; EPHB6; SPTBN2; DNM1; GNAI3; PEBP1; EPHA1; HBEGF; SEMA5A
BCR signaling pathway
POU2F2; MALT1; IBTK; NETO2; CSNK2A1; CSK; PAG1; MAP4K1; DOK1
BDNF signaling pathway
EGR1; DOK5; EGR2; CDH2; CNR1; CDKL5; SIRPA; CSNK2A1; EEF2; IGF2BP1
Cell Cycle
CSNK1E; SPC24; CDC25B; GADD45AB; CNEP1R1; CENPN; RBBP8; CDKN2B; MDM2; NUP50
Cell Cycle, Mitotic
SET; BLZF1; ENSA; DYRK1A; KIF2B; LMNB1; MLF1IP; CDK11A; MIS12; SGOL2
Condensation of Prometaphase Chromosomes
CSNK2A2; NCAPH; NCAPG; SMC2; SMC4; NCAPD2; CSNK2B; CSNK2A1

Protein Function

CSNK2A1 has several biochemical functions, for example, ATP binding, Hsp90 protein binding, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSNK2A1 itself. We selected most functions CSNK2A1 had, and list some proteins which have the same functions with CSNK2A1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CAMK2D1; ACSM3; UBE2D2A; RNASEL; PPP2R4; GLUL; UCKL1; MAT2AB; FARSA; TAF1
Function Hsp90 protein binding
Related Protein UNC45B; USP19; FKBP6; RPS3; CDC37; PPID; NPAS2; NASP; CHORDC1; UNC45A
Function protein N-terminus binding
Related Protein TARBP2; PHB2; EXOC4; TAF11; DCN; NTSR1; NPAT; SCT; TBL1XR1; ERCC5
Function protein binding
Related Protein CST1; TXNDC12; POP4; SPTAN1; TBC1D19; OIT3; LSM5; ZDHHC13; SLX4IP; ULK1
Function protein serine/threonine kinase activity
Related Protein ACVR2AA; ZNF143B; NIM1; PIK3CA; DYRK1B; CDKL5; CDC42BPG; SIK2; GRK1A; BUB1B

Interacting Protein

CSNK2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSNK2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSNK2A1.
CSNK2B; PTPN1; CSNK2A2