cst5
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  • Official Full Name
  • cystatin D
  • Background
  • The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.
  • Synonyms
  • CST5; cystatin D; cystatin-D; CST 5; Cystatin 5; CystatinD; Cysteine proteinase inhibitor; MGC71922; cystatin-5; cysteine-proteinase inhibitor
Cat.#:CST5-2028HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CST5 Protein, GST-tagged
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Cat.#:CST5-102HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CST5, His-tagged
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Cat.#:CST5-1663HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CST5 protein, His & T7-tagged
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Cat.#:CST5-494HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human CST5, His-tagged
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Cat.#:CST5-675HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CST5, His tagged
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Cat.#:CST5-3027HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CST5 cell lysate
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Involved Pathway

CST5 involved in several pathways and played different roles in them. We selected most pathways CST5 participated on our site, such as Endochondral Ossification, Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CST5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endochondral Ossification
PTHLH; PTHLHA; NKX3.2; MMP13; COL10A1A; DDR2; IFT88; CTSL2; ADAMTS1; CDKN1C
Salivary secretion
CALML3; BST1; PLCB2; Slc4a2; AMY1A; DMBT1; PRKG1; ATP2B4; AMY1B; CALM3

Protein Function

CST5 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CST5 itself. We selected most functions CST5 had, and list some proteins which have the same functions with CST5. You can find most of the proteins on our site.
Function
Related Protein
Function cysteine-type endopeptidase inhibitor activity
Related Protein CARD16; CSTL1; WFDC2; BIRC5B; KNG1; PTTG1; NGP; SERPINB4; CST4; CST9
Function protein binding
Related Protein MED20; MARK3; HADHB; Mill2; INADL; PIN4; BMI1; FANCI; GMPPB; TRIM72

CST5 Related Articles

Gorodkiewicz, E; Sankiewicz, A; et al. Surface plasmon resonance imaging biosensors for aromatase based on a potent inhibitor and a specific antibody: Sensor development and application for biological material. CENTRAL EUROPEAN JOURNAL OF CHEMISTRY 12:557-567(2014).
Ganeshnarayan, K; Velliyagounder, K; et al. Human salivary cystatin SA exhibits antimicrobial effect against Aggregatibacter actinomycetemcomitans. JOURNAL OF PERIODONTAL RESEARCH 47:661-673(2012).