ctdsp1
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  • Official Full Name
  • CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
  • Background
  • This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • CTDSP1; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; NLIIF; nuclear LIM interactor interacting factor; SCP1; small CTD phosphatase 1; NLI-
Cat.#:CTDSP1-2060HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CTDSP1 Protein, GST-tagged
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Cat.#:CTDSP1-28022THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CTDSP1, His-tagged
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Cat.#:CTDSP1-4017MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CTDSP1 Protein
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Cat.#:CTDSP1-1074RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CTDSP1 Protein, His-tagged
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Cat.#:CTDSP1-7210HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CTDSP1 293 Cell Lysate
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Cat.#:CTDSP1-7211HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CTDSP1 293 Cell Lysate
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Involved Pathway

CTDSP1 involved in several pathways and played different roles in them. We selected most pathways CTDSP1 participated on our site, such as BMP receptor signaling, Coregulation of Androgen receptor activity, Regulation of cytoplasmic and nuclear SMAD2/3 signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTDSP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
BMP receptor signaling
RGMB; CTDSP1; CTDSP2; CALML4; CTDSPL; CHRDL1; RGMA; NOG; FST; SKI
Coregulation of Androgen receptor activity
CMTM2; PATZ1; KDM4C; CARM1; TMF1; PIAS3; CMTM2A; PA2G4; KDM1A; KDM3A
Regulation of cytoplasmic and nuclear SMAD2/3 signaling
CTDSPL; CTDSP2; CTDSP1

Protein Function

CTDSP1 has several biochemical functions, for example, CTD phosphatase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTDSP1 itself. We selected most functions CTDSP1 had, and list some proteins which have the same functions with CTDSP1. You can find most of the proteins on our site.
Function
Related Protein
Function CTD phosphatase activity
Related Protein CTDSP2; CTDSPL; CTDP1; RPAP2; SSU72; CTDSPLB; CTDSP1; PPM1M; CTDSPLA
Function metal ion binding
Related Protein COX5A; EGR2A; Reln; STK24; PVALB5; LHX6; AGFG1A; TGFBR1B; TOE1; RORCB
Function protein binding
Related Protein ISOC1; REV1; CXXC5; DPP4; LANCL1; TMED2; FAM54A; TTC3; OLA1; GTF2H4

Interacting Protein

CTDSP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTDSP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTDSP1.
CDCA3; MBP; Ctdsp1