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CYFIP2

  • Official Full Name

    cytoplasmic FMR1 interacting protein 2

  • Overview

    CYFIP2 is involved in T cell adhesion and p53 dependent induction of apoptosis. It does not bind RNA but is up regulated significantly in CD4+ T lymphocytes from patients with multiple sclerosis. There are 2 isoforms produced by alternative splicing.
  • Synonyms

    CYFIP2; cytoplasmic FMR1 interacting protein 2; PIR121; cytoplasmic FMR1-interacting protein 2; p53-inducible protein 121;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYFIP2-2229H Recombinant Human CYFIP2 Protein, GST-tagged Wheat Germ GST
Human CYFIP2-2268HF Recombinant Full Length Human CYFIP2 Protein, GST-tagged In Vitro Cell Free System GST 1253 amino acids
Human CYFIP2-3395H Recombinant Human CYFIP2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CYFIP2-3599H Recombinant Human CYFIP2 protein, His-tagged E.coli His 855-1253 aa
Mouse CYFIP2-4138M Recombinant Mouse CYFIP2 Protein Mammalian Cell His
Mouse CYFIP2-2122M Recombinant Mouse CYFIP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cyfip2-2407M Recombinant Mouse Cyfip2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CYFIP2-2122M-B Recombinant Mouse CYFIP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CYFIP2-1131R Recombinant Rhesus monkey CYFIP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CYFIP2-956R Recombinant Rhesus Macaque CYFIP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CYFIP2-956R-B Recombinant Rhesus Macaque CYFIP2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CYFIP2-5649Z Recombinant Zebrafish CYFIP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CYFIP2 Related Articles

CYFIP2 involved in several pathways and played different roles in them. We selected most pathways CYFIP2 participated on our site, such as RNA transport, Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYFIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportEIF4A1A;GEMIN2;SMN;NCBP2;SEH1L;EIF3H;NDC1;DDX39B;NCBP1
Regulation of actin cytoskeletonMLCK2;PPP1R12C;CHRM5B;RAF1B;FGF14;RHOAC;MAP2K1;ITGA6B;ABI2B

CYFIP2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYFIP2 itself. We selected most functions CYFIP2 had, and list some proteins which have the same functions with CYFIP2. You can find most of the proteins on our site.

Function Related Protein
protein bindingPAICS;UCKL1;NOC2L;PLEKHG6;MEI4;CABP1;DCDC2B;PCID2;CCT4

CYFIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYFIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYFIP2.

Atp6v1a; Dlg4; Dmxl2; Abi1; Ywhab

Abekhoukh, S; Bardoni, B; et al. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. FRONTIERS IN CELLULAR NEUROSCIENCE 8:-(2014).
Bozdagi, O; Sakurai, T; et al. Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice. PLOS ONE 7:-(2012).
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