cyp4v2
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  • Official Full Name
  • cytochrome P450, family 4, subfamily V, polypeptide 2
  • Background
  • This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy.
  • Synonyms
  • CYP4V2; cytochrome P450, family 4, subfamily V, polypeptide 2; cytochrome P450 4V2; CYP4AH1; BCD; CYP4V 2; Retina CYP4V2
Cat.#:CYP4V2-2287HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CYP4V2 Protein, GST-tagged
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Cat.#:CYP4V2-1165RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CYP4V2 Protein, His-tagged
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Cat.#:CYP4V2-1179CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CYP4V2
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Cat.#:CYP4V2-440HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CYP4V2 cell lysate
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Involved Pathway

CYP4V2 involved in several pathways and played different roles in them. We selected most pathways CYP4V2 participated on our site, such as cytochrome P450, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4V2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cytochrome P450
CYP2W1; CYP4Z1; CYB5B; CYB5R3; CYB5A; CYP20A1; POR; CYP4V2; CYP2A7; CYP4F12
metapathway biotransformation
CYP2W1; CYP4Z1; HS3ST4; SULT1C4; GAL3ST4; KCNAB1; NAT8B; CEACAM21; GAL3ST3; NAA20

Protein Function

CYP4V2 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4V2 itself. We selected most functions CYP4V2 had, and list some proteins which have the same functions with CYP4V2. You can find most of the proteins on our site.
Function
Related Protein
Function heme binding
Related Protein CYP2B6; CYP2A7; JAK2; HBAE1; CYP46A1.3; CBS; CYP27C1; CYP2C38; CYP2AA7; CYP4A11
Function iron ion binding
Related Protein CYP26B1; FAM125B; CYP2B19; TPH2; LCN2; CYP2W1; OGFOD2; ALOX8; CYP4B1; CYP46A1.2
Function monooxygenase activity
Related Protein CYP2AD6; CYP2AA12; CYP4V2; CYP3A4; CYP2P6; CYP4F18; CYP2F1; CYP7A1A; TYR; CYP4F14
Function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Related Protein CYP2X10.2; CYP2J5; CYP1D1; CYP2P7; CYP8B1; CYP2P8; CYP2X9; CYP2C38; CYP2C50; CYP19A1A

Interacting Protein

CYP4V2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4V2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4V2.
ZNF420

CYP4V2 Related Articles

Efstathiou, E; Titus, M; et al. Molecular Characterization of Enzalutamide-treated Bone Metastatic Castration-resistant Prostate Cancer. EUROPEAN UROLOGY 67:53-60(2015).
Takahashi, K; Kishimoto, Y; et al. Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1840:2289-2298(2014).