| Official Full Name | cysteine-rich, angiogenic inducer, 61 |
| Background | The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011] |
| Synonyms | CYR61; cysteine-rich, angiogenic inducer, 61; CCN1; GIG1; IGFBP10; protein CYR61; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10; |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
CYR61 involved in several pathways and played different roles in them. We selected most pathways CYR61 participated on our site, such as Hypertrophy Model, Oncostatin M Signaling Pathway, Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYR61 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hypertrophy Model | ANKRD1; DUSP14; WDR1; ZEB1B; MSTN; JUND; CYR61; MYOG; ADAM10A; IFRD1 |
| Oncostatin M Signaling Pathway | CYR61; JUND |
| Regulation of Wnt-mediated beta catenin signaling and target gene transcription | TLE1; ZCCHC12; MYOG; CDX1; TNIK; CYR61; CBY1; CDX4; T; AES |
| RhoA signaling pathway | MKL1; DIAPH1; CYR61; ACTA1 |
| amb2 Integrin signaling | MST1R; CYR61; HP; LPA; ELANE; MST1; NIPAL1 |
CYR61 has several biochemical functions, for example, extracellular matrix binding, heparin binding, insulin-like growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYR61 itself. We selected most functions CYR61 had, and list some proteins which have the same functions with CYR61. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix binding | FBLN2; VEGFA; CD248; SID4; SPARC; SPP1; DMP1; ITGB3; SPOCK2; TGFBI |
| heparin binding | EPYC; ECM2; PCOLCE; ABP1; BMP7; RPL29; ZNF207; TENM1; CTGF; PTN |
| insulin-like growth factor binding | CTGF; CTGFA; HTRA4; HTRA3; IGFBP6A; IGF1RA; KAZALD1; WISP3; IGFBP6B; IGFBP5B |
| integrin binding | ITGB1BP2; FERMT3; MFGE8; Npnt; ADAM22; COL3A1; ADAM10; ANGPTL3; ACTN3; WISP2 |
CYR61 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYR61 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYR61.
ZWINT; Mis12; recB; recN; MYC; CNTROB
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