Recombinant Human CYR61 protein, Fc-tagged
Cat.No. : | CYR61-896H |
Product Overview : | Recombinant Human CYR61(Thr25-Asp381) fused with Fc tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Protein length : | Thr25-Asp381 |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | CYR61 cysteine-rich, angiogenic inducer, 61 [ Homo sapiens ] |
Official Symbol : | CYR61 |
Synonyms : | CYR61; cysteine-rich, angiogenic inducer, 61; IGFBP10; protein CYR61; CCN1; GIG1; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10; |
Gene ID : | 3491 |
mRNA Refseq : | NM_001554 |
Protein Refseq : | NP_001545 |
MIM : | 602369 |
UniProt ID : | O00622 |
Chromosome Location : | 1p22.3 |
Pathway : | Hypertrophy Model, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; RhoA signaling pathway, organism-specific biosystem; amb2 Integrin signaling, organism-specific biosystem; |
Function : | extracellular matrix binding; heparin binding; insulin-like growth factor binding; integrin binding; |
Products Types
◆ Recombinant Protein | ||
CYR61-1418R | Recombinant Rat CYR61 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYR61-2165M | Recombinant Mouse CYR61 Protein, His (Fc)-Avi-tagged | +Inquiry |
CYR61-2295H | Recombinant Human CYR61 Protein, GST-tagged | +Inquiry |
Cyr61-437M | Recombinant Mouse Cyr61 Protein, His-tagged | +Inquiry |
CYR61-436H | Recombinant Human CYR61 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CYR61-7097HCL | Recombinant Human CYR61 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionRecent studies have found that CYR61 plays an important role in tumor development and metastasis, especially in cancers such as non-small cell lung cancer, breast cancer, gastric cancer, and colorectal cancer.
There are currently no drugs specifically targeting CYR61, but some anti-tumor drugs can inhibit the expression level of CYR61, such as chemotherapy drugs and targeted therapy drugs.
Studies have shown that high levels of CYR61 expression are associated with decreased patient survival, suggesting that it may be used as a biomarker to predict patient survival.
CYR61 is involved in a variety of signaling pathways, including Wnt, MAPK, ERK, and PI3K.
Regulating the expression level of CYR61 is of great significance for the treatment of diseases, especially for the treatment of cancer, and can slow down the growth and spread of tumors by inhibiting the expression level of CYR61.
The relationship between CYR61 expression levels and disease risk can be assessed by immunohistochemistry or western blot analysis of the patient's tissue samples.
Customer Reviews (3)
Write a reviewIt has good effect and stability in gene expression regulation.
Will not interact with other drugs, will not affect.
The application performance is stable in common colorimetric reactions.
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