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Recombinant Human CYR61 protein, GST-tagged

Cat.No. : CYR61-3656H
Product Overview : Recombinant Human CYR61 protein(165-239 aa), fused to GST tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
Protein length : 165-239 aa
AA Sequence : EDSIKDPMEDQDGLLGKELGFDASE VELTRNNELIAVGKGSSLKRLPVFG MEPRILYNPLQGQKCIVQTTSWSQC
Purity : 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : CYR61 cysteine-rich, angiogenic inducer, 61 [ Homo sapiens ]
Official Symbol : CYR61
Synonyms : CYR61; cysteine-rich, angiogenic inducer, 61; IGFBP10; protein CYR61; CCN1; GIG1; IBP-10; IGFBP-10; CCN family member 1; IGF-binding protein 10; cysteine-rich, anigogenic inducer, 61; cysteine-rich heparin-binding protein 61; insulin-like growth factor-binding protein 10;
Gene ID : 3491
mRNA Refseq : NM_001554
Protein Refseq : NP_001545
MIM : 602369
UniProt ID : O00622

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What did recent research on CYR61 find? 10/09/2021

Recent studies have found that CYR61 plays an important role in tumor development and metastasis, especially in cancers such as non-small cell lung cancer, breast cancer, gastric cancer, and colorectal cancer.

Which drugs can inhibit the expression level of CYR61? 03/03/2021

There are currently no drugs specifically targeting CYR61, but some anti-tumor drugs can inhibit the expression level of CYR61, such as chemotherapy drugs and targeted therapy drugs.

What is the relationship between the level of CYR61 expression and patient survival? 02/08/2021

Studies have shown that high levels of CYR61 expression are associated with decreased patient survival, suggesting that it may be used as a biomarker to predict patient survival.

What signaling pathways is CYR61 involved in? 12/26/2020

CYR61 is involved in a variety of signaling pathways, including Wnt, MAPK, ERK, and PI3K.

What is the significance of regulating the expression level of CYR61 for the treatment of diseases? 06/03/2020

Regulating the expression level of CYR61 is of great significance for the treatment of diseases, especially for the treatment of cancer, and can slow down the growth and spread of tumors by inhibiting the expression level of CYR61.

How can the relationship between CYR61 expression levels and disease risk be assessed? 02/24/2020

The relationship between CYR61 expression levels and disease risk can be assessed by immunohistochemistry or western blot analysis of the patient's tissue samples.

Customer Reviews (3)

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07/18/2022

    It has good effect and stability in gene expression regulation.

    06/04/2022

      Will not interact with other drugs, will not affect.

      07/20/2021

        The application performance is stable in common colorimetric reactions.

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