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Calcineurin

Calcineurin involved in several pathways and played different roles in them. We selected most pathways Calcineurin participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Calcineurin were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

Calcineurin has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Calcineurin itself. We selected most functions Calcineurin had, and list some proteins which have the same functions with Calcineurin. You can find most of the proteins on our site.

Function Related Protein

Calcineurin has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Calcineurin here. Most of them are supplied by our site. Hope this information will be useful for your research of Calcineurin.

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Q&As (5)

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How does Calcineurin contribute to synaptic plasticity and memory formation? 03/12/2022

Calcineurin is involved in dephosphorylating proteins that play a role in synaptic plasticity, which is crucial for learning and memory.

How is Calcineurin related to the immune system and immunosuppressive drugs? 09/06/2021

Calcineurin is a target for immunosuppressive drugs like cyclosporine and tacrolimus, which inhibit its activity. This is important in preventing organ transplant rejection and treating autoimmune diseases.

What are the side effects and limitations of immunosuppressive drugs that target Calcineurin? 06/07/2021

Side effects may include increased susceptibility to infections and kidney toxicity. Long-term use may lead to adverse effects, and not all patients respond to these drugs.

What is the chemical structure of Calcineurin, and how does it interact with calcium and calmodulin? 01/15/2020

Calcineurin is a heterodimeric protein composed of a catalytic subunit (CnA) and a regulatory subunit (CnB). It interacts with calcium ions and calmodulin, which bind to CnB, activating the phosphatase activity of CnA.

What is the role of Calcineurin in T cell activation and the immune response? 03/29/2018

Calcineurin is a key component of the T cell receptor signaling pathway. It activates transcription factors like NFAT, which control the expression of genes involved in the immune response.

Customer Reviews (3)

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Reviews
05/18/2020

    The product I ordered arrived promptly, and I'm impressed with the efficiency."

    11/02/2018

      I'm thoroughly satisfied with the product, it made my lab work so much easier.

      03/17/2018

        The product I received for my experiments was of the highest quality.

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