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DEFB4

  • Official Full Name

    defensin beta 4

  • Overview

    Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.
  • Synonyms

    BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102; beta-defensin 4A; defensin, beta 2; defensin, beta 4; OTTHUMP00000159651; skin-antimicrobial peptide 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DEFB4-18H Active Recombinant Human DEFB4 protein(1-50aa) E.coli N/A 1-50aa
Mouse DEFB4-4486M Recombinant Mouse DEFB4 Protein Mammalian Cell His
Mouse DEFB4-2314M Recombinant Mouse DEFB4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DEFB4-1953M Recombinant Mouse DEFB4 Protein (23-63 aa), His-SUMO-tagged E.coli His/SUMO 23-63 aa
Mouse DEFB4-2314M-B Recombinant Mouse DEFB4 Protein Pre-coupled Magnetic Beads HEK293
Rat Defb4-8655R Active Recombinant Rat Defb4 E.coli N/A
Rat Defb4-598R Recombinant Rat Defb4 protein E.coli N/A 41
Rat DEFB4-1838R Recombinant Rat DEFB4 Protein Mammalian Cell His
Rat DEFB4-1496R-B Recombinant Rat DEFB4 Protein Pre-coupled Magnetic Beads HEK293
Rat DEFB4-1496R Recombinant Rat DEFB4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi

DEFB4 involved in several pathways and played different roles in them. We selected most pathways DEFB4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DEFB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DEFB4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DEFB4 itself. We selected most functions DEFB4 had, and list some proteins which have the same functions with DEFB4. You can find most of the proteins on our site.

Function Related Protein

DEFB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEFB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DEFB4.

  • Q&As
  • Reviews

Q&As (6)

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Is the expression of DEFB4 affected by environmental factors? 11/16/2022

Yes, the expression of DEFB4 is affected by environmental factors, such as nutritional status, inflammation level, microbial infection, etc.

How to regulate DEFB4 expression? 07/17/2022

DEFB4 expression can be regulated by techniques such as gene knockout, gene silencing, or gene transduction. In addition, environmental factors (e.g., nutrition, inflammation, etc.) can also affect its expression levels.

Are there other coding variants of DEFB4? 03/10/2021

Yes, there are other coding variants of DEFB4 that may have different functions and expression patterns.

What is the significance of studying DEFB4? 08/11/2020

Studying DEFB4 can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.

What is the relationship between DEFB4 and muscle atrophy? 04/16/2020

Studies have shown that DEFB4 can inhibit the occurrence of muscle atrophy, but the specific mechanism is not yet clear.

What are the applications of DEFB4 in drug discovery? 12/01/2019

DEFB4 can be used as a target for the development of new drugs, or as a drug carrier for the directional delivery of drugs.

Customer Reviews (3)

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Reviews
04/15/2022

    Under the influence of temperature, humidity and light, this protein is stable and durable.

    03/29/2022

      DEFB4 is immunogenic and allergenic, which is even more important for proteins used in drug development.

      05/02/2021

        The consistency and reliability of this protein are good.

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