dnaja1
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  • Official Full Name
  • DnaJ (Hsp40) homolog, subfamily A, member 1
  • Background
  • DnaJ homolog subfamily A member 1 is a protein that in humans is encoded by the DNAJA1 gene.
  • Synonyms
  • DNAJA1; DnaJ (Hsp40) homolog, subfamily A, member 1; HSJ2; dnaJ homolog subfamily A member 1; dj 2; hdj 2; HSPF4; NEDD7; neural precursor cell expressed; developmentally down regulated 7; HSJ-2; human DnaJ protein 2; heat shock protein J2; dnaJ protein ho
Cat.#:DNAJA1-2725HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNAJA1 Protein, GST-tagged
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Cat.#:DNAJA1-12054HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJA1, GST-tagged
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Cat.#:DNAJA1-2131HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DnaJ (Hsp40) Homolog, Subfamily A, Member 1
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Cat.#:DNAJA1-29210THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJA1
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Cat.#:DNAJA1-4679MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DNAJA1 Protein
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Cat.#:DNAJA1-1900RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DNAJA1 Protein
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Cat.#:DNAJA1-2157CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNAJA1
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Cat.#:DNAJA1-10061ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNAJA1
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Cat.#:DNAJA1-6895HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNAJA1 293 Cell Lysate
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Involved Pathway

DNAJA1 involved in several pathways and played different roles in them. We selected most pathways DNAJA1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein processing in endoplasmic reticulum
ERO1LB; HSPA1B; DNAJC5GB; BAXA; UBE2D1A; UBE2J1; SEC61AL2; HSPH1; UBE2G1A; SAR1AB

Protein Function

DNAJA1 has several biochemical functions, for example, ATP binding, C3HC4-type RING finger domain binding, G-protein coupled receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJA1 itself. We selected most functions DNAJA1 had, and list some proteins which have the same functions with DNAJA1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PDGFRB; STK25; CDKL1; MYH10; DYRK1AA; ATP1A1A.4; RAD51B; SRC; BAT1; EIF2AK3
Function C3HC4-type RING finger domain binding
Related Protein HSPA1B; HSPA8; KCNH2; HSPA1A; DNAJA1; PINK1
Function G-protein coupled receptor binding
Related Protein RLN3; GNAI2B; HSPA8; UTS2D; ITGB4; NPFF; HSPA1A; GNA14; PSAP; RSPO3
Function Hsp70 protein binding
Related Protein CDKN1B; DNAJA1; ERN1; DNAJC10; PARK2; DNAJC2; PPID; C11orf73; DNAJB2; TSACC
Function chaperone binding
Related Protein RNF207; DNAJB5; HSP104; HSPD1; HSCB; DNAJB1; TIMM9; TIMM44; TBCC; PFDN6
Function low-density lipoprotein particle receptor binding
Related Protein APOEB; LRPAP1; MMP13; APOA5; SYT1; APOE; SACS; ARRB2; LRP2; SLC9A3R2
Function metal ion binding
Related Protein FTR54; RASA3; ZBTB41; RAD50; SDF4; NDUFS2; CYGB1; ZNF35; PM20D1; ADIPOR1
Function protein binding
Related Protein KCNE3; ING4; S100A13; APLP1; CNO; STK40; RBM12B; XPA; IL12A; YWHAB
Function ubiquitin protein ligase binding
Related Protein HERC2; RBX1; ARIH1; LRPPRC; ANKRD32; SCAMP3; HSPA9; PER3; PARK2; HSPA1B
Function unfolded protein binding
Related Protein HSP90AA1; AFG3L2; CLPXA; HTRA2; PDRG1; TBCA; AIP; TCP1; NPM1; ERLEC1

Interacting Protein

DNAJA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJA1.
LSM2; HDAC6; AICDA; SAP18; MAP3K7; PTP4A3; Tuba1b; TNFRSF1A; TNFRSF1B; HLA-B; UQCRC1; Tubb4b; Tubg1

DNAJA1 Related Articles

Kotlarz, A; Tukaj, S; et al. Human Hsp40 proteins, DNAJA1 and DNAJA2, as potential targets of the immune response triggered by bacterial DnaJ in rheumatoid arthritis. CELL STRESS & CHAPERONES 18:653-659(2013).
Orthwein, A; Zahn, A; et al. Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1. EMBO JOURNAL 31:679-691(2012).