| Official Full Name | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| Background | DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone;activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J;domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4;motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 (PubMed 11147971)). |
| Synonyms | DNAJC6; DnaJ (Hsp40) homolog, subfamily C, member 6; putative tyrosine-protein phosphatase auxilin; auxilin; KIAA0473; dnaJ homolog subfamily C member 6; DnaJ (Hsp40) homolog, subfamily B, member 6; DJC6; MGC48436; MGC129914; MGC129915 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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DNAJC6 involved in several pathways and played different roles in them. We selected most pathways DNAJC6 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | CXCR2; CAPZA2; VPS24; RAB5B; SMURF1; TGFB1A; TSG101; EEA1; CHMP6B; RAB11FIP4A |
DNAJC6 has several biochemical functions, for example, SH3 domain binding, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC6 itself. We selected most functions DNAJC6 had, and list some proteins which have the same functions with DNAJC6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3 domain binding | ARHGAP6; FMNL3; USP8; CBLC; MAPK15; LANCL1; LYN; SH3BGRL2; SH3BP2; ABI2 |
| protein tyrosine phosphatase activity | RNGTT; DUSP13; CDC14C; DUSP18; MDP1; DUSP28; PALD1; CDC14AA; PALD1B; PTPMT1 |
DNAJC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC6.
BAG2
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