Recombinant Human DNAJC6, GST-tagged

• Cat.No.: DNAJC6-12089H
• Product Overview: Recombinant Human DNAJC6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 387-733a.a.
• Description: DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 [ Homo sapiens ]
• Official Symbol: DNAJC6
• Synonyms: DNAJC6; DnaJ (Hsp40) homolog, subfamily C, member 6; putative tyrosine-protein phosphatase auxilin; auxilin; KIAA0473; dnaJ homolog subfamily C member 6; DnaJ (Hsp40) homolog, subfamily B, member 6; DJC6; MGC48436; MGC129914; MGC129915
• Gene ID: 9829
• mRNA Refseq: NM_001256864
• Protein Refseq: NP_001243793
• MIM: 608375
• UniProt ID: O75061
• Chromosome Location: 1p31.3
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem
• Function: SH3 domain binding; heat shock protein binding; hydrolase activity; protein tyrosine phosphatase activity