Recombinant Human DNAJC6, GST-tagged
Cat.No. : | DNAJC6-12089H |
Product Overview : | Recombinant Human DNAJC6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]). |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 387-733a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 [ Homo sapiens ] |
Official Symbol : | DNAJC6 |
Synonyms : | DNAJC6; DnaJ (Hsp40) homolog, subfamily C, member 6; putative tyrosine-protein phosphatase auxilin; auxilin; KIAA0473; dnaJ homolog subfamily C member 6; DnaJ (Hsp40) homolog, subfamily B, member 6; DJC6; MGC48436; MGC129914; MGC129915; |
Gene ID : | 9829 |
mRNA Refseq : | NM_001256864 |
Protein Refseq : | NP_001243793 |
MIM : | 608375 |
UniProt ID : | O75061 |
Chromosome Location : | 1p31.3 |
Pathway : | Clathrin derived vesicle budding, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem; |
Function : | SH3 domain binding; heat shock protein binding; hydrolase activity; protein tyrosine phosphatase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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