dner
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  • Official Full Name
  • delta/notch-like EGF repeat containing
  • Background
  • Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.
  • Synonyms
  • DNER; delta/notch-like EGF repeat containing; delta and Notch-like epidermal growth factor-related receptor; bet; UNQ26; Brain EGF repeat-containing transmembrane protein; Bret; Delta/notch-like EGF-related receptor; DNER_HUMAN; Transmembrane protein Bet; H_NH0150O02.1; OTTHUMP00000204223; WUGSC:H_NH0150O02.1; delta-notch-like EGF repeat-containing transmembrane
Cat.#:DNER-2784HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNER Protein, GST-tagged
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Cat.#:Dner-410MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Delta/Notch-Like EGF-Related Receptor
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Cat.#:DNER-1812HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNER protein, His & T7-tagged
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Cat.#:DNER-26158THTag:Flag
Source (Host):HEK293Species:Human
Product nameRecombinant Human DNER, FLAG-tagged
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Cat.#:DNER-28368THTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human DNER, Fc-tagged
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Cat.#:DNER-821HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human DNER Protein, Fc Chimera
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Cat.#:DNER-835HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human DNER
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Cat.#:DNER-4733MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DNER Protein
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Cat.#:Dner-838MTag:Fc
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Dner Protein, Fc Chimera
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Cat.#:DNER-8380ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNER
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Cat.#:DNER-2080HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human Delta/notch-like EGF Repeat Containing, Fc Chimera
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Involved Pathway

DNER involved in several pathways and played different roles in them. We selected most pathways DNER participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Notch signaling pathway, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNER were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activated NOTCH1 Transmits Signal to the Nucleus
MIB1; JAG1; DNER; CNTN1; JAG2; DTX2; DLK1; ADAM10
Notch signaling pathway
HDAC2; LFNG; DLK1; NOTCH4; MYCBP; DLL4; NUMB; NOTCH1B; NUMBL; DTX2
Signal Transduction
OR52B4; ARHGEF25; MYO7A; CRHB; BCL9; CRABP2; GREM2; ABCA4A; SDR9C7; OPN5
Signaling by NOTCH
RAB6A; MDKB; TLE4; DLK1; TLE3; TLE2; MDK; MDKA; DNER; HEYL
Signaling by NOTCH1
DNER; DLK1; TLE3; HEYL; DTX2

Protein Function

DNER has several biochemical functions, for example, Notch binding, calcium ion binding, clathrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNER itself. We selected most functions DNER had, and list some proteins which have the same functions with DNER. You can find most of the proteins on our site.
Function
Related Protein
Function Notch binding
Related Protein SNW1; AAK1; NOTCH4; DLL4; NCOR2; JAG1B; ADAM17; JAG2B; DNER; HIF1AN
Function calcium ion binding
Related Protein CHP1; ANXA2; S100A6; SLIT1; KCNIP2; ACTN4; CD93; GUCA1E; RASGRP2; PCLO
Function clathrin binding
Related Protein NCALD; DOC2B; SYT5; RPH3A; SYT1; TOM1; DOC2D; AFTPH; SYTL3; SYT4
Function protein binding
Related Protein EVI5L; TBC1D17; MAPRE3; GNMT; BCCIP; MOBKL1A; BPIFA2; KIAA0408; TEX10; SIGLEC8
Function transmembrane signaling receptor activity
Related Protein LILRB5; CLDN4; CLDN3; CELSR1; GP6; CD247; FZD8A; Fzd4; P2RX6; AGER

Interacting Protein

DNER has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNER here. Most of them are supplied by our site. Hope this information will be useful for your research of DNER.
ZNF24

DNER Related Articles

Honnorat, J; et al. Therapeutic approaches in antibody-associated central nervous system pathologies. REVUE NEUROLOGIQUE 170:587-594(2014).
Greene, M; Lai, YJ; et al. DNER Antibodies in Patients with Anti-Tr, Paraneoplastic Cerebellar Degeneration, and Hodgkin's Lymphoma. ANNALS OF NEUROLOGY 76:S78-S78(2014).