dnmt3l
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  • Official Full Name
  • DNA (cytosine-5-)-methyltransferase 3-like
  • Background
  • DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands.
  • Synonyms
  • DNMT3L; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; cytosine 5 methyltransferase 3 like protein; human cytosine 5 methyltransferase 3 like protein; MGC1090; cytosine-5-methyltransferase 3-like protein; human cyto
Cat.#:DNMT3L-2794HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNMT3L Protein, GST-tagged
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Cat.#:DNMT3L-12111HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
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Cat.#:DNMT3L-141HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
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Cat.#:DNMT3L-166HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DNMT3L, GST-tagged
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Cat.#:DNMT3L-203HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
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Cat.#:DNMT3L-26950THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human DNMT3L
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Cat.#:DNMT3L-6951HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DNMT3L, GST-tagged
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Cat.#:DNMT3L-930HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human DNMT3L Protein, DDK-tagged
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Cat.#:DNMT3L-1927RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DNMT3L Protein
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Cat.#:DNMT3L-6852HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNMT3L 293 Cell Lysate
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Cat.#:DNMT3L-6853HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNMT3L 293 Cell Lysate
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Involved Pathway

DNMT3L involved in several pathways and played different roles in them. We selected most pathways DNMT3L participated on our site, such as DNA methylation, Epigenetic regulation of gene expression, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNMT3L were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA methylation
DNMT3B; UHRF1; DNMT3A; DNMT1; DNMT3L
Epigenetic regulation of gene expression
RRP8; SAP30BP; SUZ12A; TAF1D; SAP18; H3F3D; CD3EAP; BAZ2A; TAF1B; TET2
Gene Expression
SESN3; CCNT2B; PTRFB; TRMT12; JARID2B; ZNF75D; SAP30BP; TET1; EFCAB11; ZNF70
Trans-sulfuration and one carbon metabolism
MTHFD2; DNMT3L

Protein Function

DNMT3L has several biochemical functions, for example, enzyme activator activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNMT3L itself. We selected most functions DNMT3L had, and list some proteins which have the same functions with DNMT3L. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme activator activity
Related Protein GMFG; SAE1; SLX4; PITRM1; MMP17; MMP15; ARL1; ALDH1A2; PRKCE; GTF3C4
Function enzyme binding
Related Protein YWHAH; MLEC; HDAC2; NCOA1; HSPA6; HSPA2; PTPLAD1; NPM2; CBX3; MDM2
Function metal ion binding
Related Protein PKM; ACACB; ACAP3B; HRG; IRF2BP2A; PGM2L1; ZNF438; ANKIB1; NT5C2L1; ZNF503
Function protein binding
Related Protein RPTOR; MC5R; FANCL; NCKAP1; CTCF; LOXL2; BAG6; PDGFRA; FSHB; MUSK

Interacting Protein

DNMT3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNMT3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DNMT3L.
RSL24D1; HDAC1; Dnmt3a; H3F3A; NUDT21; GSK3B; PHPT1