dnmt3l
Share
  • Official Full Name
  • DNA (cytosine-5-)-methyltransferase 3-like
  • Background
  • DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands.
  • Synonyms
  • DNMT3L; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; cytosine 5 methyltransferase 3 like protein; human cytosine 5 methyltransferase 3 like protein; MGC1090; cytosine-5-methyltransferase 3-like protein; human cyto
Cat.#:DNMT3L-2794HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNMT3L Protein, GST-tagged
+Inquiry
Cat.#:DNMT3L-12111HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
+Inquiry
Cat.#:DNMT3L-141HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
+Inquiry
Cat.#:DNMT3L-166HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DNMT3L, GST-tagged
+Inquiry
Cat.#:DNMT3L-203HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNMT3L, His-tagged
+Inquiry
Cat.#:DNMT3L-26950THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human DNMT3L
+Inquiry
Cat.#:DNMT3L-6951HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human DNMT3L, GST-tagged
+Inquiry
Cat.#:DNMT3L-930HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human DNMT3L Protein, DDK-tagged
+Inquiry
Cat.#:DNMT3L-1927RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DNMT3L Protein
+Inquiry
Cat.#:DNMT3L-6852HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNMT3L 293 Cell Lysate
+Inquiry
Cat.#:DNMT3L-6853HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNMT3L 293 Cell Lysate
+Inquiry

Involved Pathway

DNMT3L involved in several pathways and played different roles in them. We selected most pathways DNMT3L participated on our site, such as DNA methylation, Epigenetic regulation of gene expression, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNMT3L were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA methylation
DNMT3A; UHRF1; DNMT1; DNMT3L; DNMT3B
Epigenetic regulation of gene expression
SMARCA5; TAF1B; MTF2; TAF1C; TAF1A; SUZ12B; SAP30L; TAF1D; JARID2B; CD3EAP
Gene Expression
TUBB3; NR6A1; MED23; PHF1; APEH; ZNF560; TRMT61A; NR1I2; KHSRP; ZNF114
Trans-sulfuration and one carbon metabolism
DNMT3L; MTHFD2

Protein Function

DNMT3L has several biochemical functions, for example, enzyme activator activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNMT3L itself. We selected most functions DNMT3L had, and list some proteins which have the same functions with DNMT3L. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme activator activity
Related Protein MMP15; SFTPBB; PRKCD; PSAP; CTAGE5; SFTPB; RICTOR; PPP1R12B; CLPS; PSAPL1
Function enzyme binding
Related Protein YWHAB; TSPAN33; NR5A1; MST1R; DYM; N4BP2L2; TSPAN15; MDM2; SUDS3; GBP1
Function metal ion binding
Related Protein ZNF559-ZNF177; GM12824; TKT; ZEB1B; ITGA10; ZNF577; SCRT1A; FREM2; GIT2; CYP4F18
Function protein binding
Related Protein AMPH; TOM1; FAN1; NGF; ADAM17; TNP1; CPT1B; EIF1AD; BLOC1S3; MRPL49

Interacting Protein

DNMT3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNMT3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DNMT3L.
RSL24D1; HDAC1; Dnmt3a; H3F3A; NUDT21; GSK3B; PHPT1