dtl
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  • Official Full Name
  • denticleless homolog (Drosophila)
  • Background
  • Denticleless protein homolog is a protein that in humans is encoded by the DTL gene.
  • Synonyms
  • DTL; denticleless homolog (Drosophila); denticleless protein homolog; DCAF2; DDB1 and CUL4 associated factor 2; L2DTL; RA regulated nuclear matrix associated protein; RAMP; Lethal(2) denticleless protein homolog; CDW1; Ddb1- and Cul4-associated factor 2; Denticleless homolog; DTL_HUMAN; Retinoic acid regulated nuclear matrix associated protein; Retinoic acid-regulated nuclear matrix-associated protein; RA-regulated nuclear matrix-associated protein; CDT2
Cat.#:DTL-12186HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTL, His-tagged
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Cat.#:DTL-27914THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTL, His-tagged
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Cat.#:DTL-504HTag:GST|His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTL Protein, GST-His-tagged
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Cat.#:DTL-4850MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DTL Protein
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Cat.#:DTL-1341RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DTL Protein, His-tagged
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Cat.#:DTL-2728CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DTL
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Cat.#:DTL-9515ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DTL
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Cat.#:DTL-6801HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DTL 293 Cell Lysate
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Involved Pathway

DTL involved in several pathways and played different roles in them. We selected most pathways DTL participated on our site, such as DNA Damage Bypass, DNA Repair, Recognition of DNA damage by PCNA-containing replication complex, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA Damage Bypass
ZBTB32; POLI; SPRTN; DDB1; UBE2L6; USP43; DTL; USP10; RAD18; KIAA0101
DNA Repair
CLSPN; GEN1; SPRTN; POLD3; THRSP; YY1A; APITD1; ZBTB32; RAD17; COPS2
Recognition of DNA damage by PCNA-containing replication complex
RAD18; DTL; ZBTB32

Protein Function

DTL has several biochemical functions, for example, protein binding, contributes_to ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DTL itself. We selected most functions DTL had, and list some proteins which have the same functions with DTL. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ARNTL1A; OCRL; cgr2b; SMARCE1; Fgf15; RYR2; HSP90AA1.2; PALLD; IFT43; SPC24
Function contributes_to ubiquitin-protein transferase activity
Related Protein DTL; DBN1; KBTBD12; KLHDC5; KLHL14; RNF20; KLHL36; KLHL38; TNFAIP1; KEAP1B

Interacting Protein

DTL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTL here. Most of them are supplied by our site. Hope this information will be useful for your research of DTL.
DDB1; WDR5; Dtl; Ddb1; COPS6; CUL4A; CUL4B; GRWD1

DTL Related Articles

Urity, VB; Issaian, T; et al. Architecture of kangaroo rat inner medulla: segmentation of descending thin limb of Henle's loop. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 302:R720-R726(2012).
Dantzler, WH; Pannabecker, TL; et al. Urine concentrating mechanism in the inner medulla of the mammalian kidney: role of three-dimensional architecture. ACTA PHYSIOLOGICA 202:361-378(2011).