DTX2 Protein, deltex homolog 2 (Drosophila)


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Official Full Name deltex homolog 2 (Drosophila)
Background DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
Synonyms DTX2; deltex homolog 2 (Drosophila); deltex (Drosophila) homolog 2; protein deltex-2; RNF58; Deltex 2; Deltex2; hDTX2; Highly similar to hPMSR6 [H.sapiens]; Protein deltex 2; RING finger protein 58; Zinc ion binding protein
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DTX2-12191H Recombinant Human DTX2, GST-tagged E.coli GST
    Human DTX2-2714H Recombinant Human DTX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DTX2-513HCL Recombinant Human DTX2 cell lysate N/A
    Mouse DTX2-4857M Recombinant Mouse DTX2 Protein Mammalian Cell His
    Zebrafish DTX2-6778Z Recombinant Zebrafish DTX2 Mammalian Cell His

    DTX2 involved in several pathways and played different roles in them. We selected most pathways DTX2 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Notch Signaling Pathway, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated NOTCH1 Transmits Signal to the Nucleus CNTN1; DLK1; JAG1; JAG2; DTX2; ADAM10; DNER; MIB1
    Notch Signaling Pathway MFAP5; MFNG; DLC; DLL4; RBPJ; JAG2B; MAML1; MARK2; CTBP1; TLE3A
    Signal Transduction FOXH1; ADH8B; FMNL3; TTC21B; INTU; GPRC6A; EVL; OBSCN; GPR65; PAG1
    Signaling by NOTCH DTX2; DLK1; MDKB; MDKA; RAB6A; DNER; TLE3; TLE2; TLE4; MDK
    Signaling by NOTCH1 DNER; DTX2; TLE3; DLK1; HEYL

    DTX2 has several biochemical functions, for example, ligase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX2 itself. We selected most functions DTX2 had, and list some proteins which have the same functions with DTX2. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity SYVN1; RANBP2; TRIM21; RNF135; PCXB; TTLL11; HECW1B; TRIM8; PELI2; TRIM27
    protein binding ZNF317; RAB27A; RIC8A; HSD17B12; TNFRSF1A; BMP4; CXCR4; PLSCR3; RGS17; IL13
    zinc ion binding TRIML1; TRIM16; S100A5; MAN2C1; MMP23BB; ZNF259; RORB; ZSWIM4; RBM4.2; TRIM8

    DTX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX2.


    Blanco, J; Arevalo, F; et al. Effect of the industrial steaming on the toxicity, estimated by LC-MS/MS, of mussels exposed for a long time to diarrhetic shellfish poisoning (DSP) toxins. FOOD CHEMISTRY 177:240-247(2015).
    Garcia-Mendoza, E; Sanchez-Bravo, YA; et al. Lipophilic toxins in cultivated mussels (Mytilus galloprovincialis) from Baja California, Mexico. TOXICON 90:111-123(2014).

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