|Official Full Name||dual specificity phosphatase 19|
|Background||Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based;protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine;and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19;contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by;alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of;DUSPs (see MIM 600714) (summary by Patterson et al., 2009 (PubMed 19228121)).|
|Synonyms||DUSP19; dual specificity phosphatase 19; dual specificity protein phosphatase 19; DUSP17; SKRP1; Dual specificity phosphatase TS DSP1; Dual specificity phosphatase TS-DSP1; DUS19_HUMAN; DUSP 17; DUSP 19; LMW DSP3; LMW-DSP3; LMWDSP 3; LMWDSP3; Low molecular weight dual specificity phosphatase 3; MGC138210; Protein phosphatase SKRP1; SAPK pathway regulating phosphatase 1; SAPK pathway-regulating phosphatase 1; SKRP 1; Stress activated protein kinase pathway regulating phosphatase 1; Stress-activated protein kinase pathway-regulating phosphatase 1; TS DSP1; TS-DSP1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
DUSP19 involved in several pathways and played different roles in them. We selected most pathways DUSP19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DUSP19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
DUSP19 has several biochemical functions, for example, JUN kinase phosphatase activity, MAP-kinase scaffold activity, mitogen-activated protein kinase kinase kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DUSP19 itself. We selected most functions DUSP19 had, and list some proteins which have the same functions with DUSP19. You can find most of the proteins on our site.
|JUN kinase phosphatase activity||NT5DC3; SACM1L; SACM1LB; PXYLP1; SGPP2; SACM1LA; TENC1; CTDSPL2B; DUSP19; CTDSPL2A|
|MAP-kinase scaffold activity||CD36; MAPK8IP3; KSR1; SPAG9; MAPK8IP2; DUSP19; SPAG9A; JIP1|
|mitogen-activated protein kinase kinase kinase binding||MARVELD3; MAPK8IP3; MAPK1; TRAF6; TRAF2; TCF3; PPEF2; CDC37; MAP3K11; DUSP19|
|protein binding||PRSS3; IVL; CD200; RTF1; CALM3; MAP3K7IP3; IP6K2; NPHP3; FAM212A; CASP2|
|protein kinase activator activity||STRADA; NKX3; TOM1L1; MARK2; DAXX; FAM58A; NCKAP1L; EPO; AGAP2; MAPK8IP2|
|protein kinase inhibitor activity||JIP1; SH3BP5LA; TAOK3; NPM1; CD36; PRKRIP1; SOCS1; GMFG; SOCS5B; CAMK2N1A|
|protein tyrosine phosphatase activity||DUSP23; DUSP11; PTPRZ1; DUSP22A; DNAJC6; DUSP22B; TPTE; DUSP21; PTPN23; PTPRJ|
|protein tyrosine/threonine phosphatase activity||SACM1LB; DUSP2; SACM1LA; DUSP1; SACM1L; PXYLP1; PTPRQ; CTDSPL2B; TENC1; NT5DC3|
DUSP19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DUSP19 here. Most of them are supplied by our site. Hope this information will be useful for your research of DUSP19.