DYNLRB1 Protein, dynein, light chain, roadblock-type 1

DYNLRB1

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DYNLRB1

Official Full Name dynein, light chain, roadblock-type 1
Background DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
Synonyms km23; Dncl2a
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DYNLRB1-12233H Recombinant Human DYNLRB1, GST-tagged E.coli GST
    Human DYNLRB1-273H Recombinant Human DYNLRB1 protein, His-tagged E.coli His
    Human DYNLRB1-2750H Recombinant Human DYNLRB1, His-tagged E.coli His
    Human DYNLRB1-2976H Recombinant Human DYNLRB1 Protein, GST-tagged Wheat Germ GST
    Human DYNLRB1-6755HCL Recombinant Human DYNLRB1 293 Cell Lysate HEK293 N/A
    Mouse DYNLRB1-4914M Recombinant Mouse DYNLRB1 Protein Mammalian Cell His
    Rat DYNLRB1-1989R Recombinant Rat DYNLRB1 Protein Mammalian Cell His
    Zebrafish DYNLRB1-11405Z Recombinant Zebrafish DYNLRB1 Mammalian Cell His

    DYNLRB1 involved in several pathways and played different roles in them. We selected most pathways DYNLRB1 participated on our site, such as Assembly of the primary cilium, Intraflagellar transport, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of the primary cilium CCT3; IFT46; WDR19; KIFAP3; PCM1; TCTEX1D1; TUBB4B; HSPB11; IQCB1; KIF3B
    Intraflagellar transport IFT20; TCTEX1D2; IFT52; IFT88; IFT122; IFT172; KIFAP3B; WDR19; DYF-1; TNPO1
    Organelle biogenesis and maintenance UNC119B; MKKS; MRPS23; ICT1; AURKAIP1; BBS1; IFT52; TTC30A; MRRF; MRPL45

    DYNLRB1 has several biochemical functions, for example, identical protein binding, motor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNLRB1 itself. We selected most functions DYNLRB1 had, and list some proteins which have the same functions with DYNLRB1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding PON2; PFKFB1; NME1; ERBB3; IIGP1; HACL1; AIM2; SHARPIN; PRPF3; APLP1
    motor activity DYNC2LI1; MYL6; MYO1E; MYH9A; DYNC2H1; MYO6B; MYO1F; MYO7B; MYH7B; MYH9
    protein binding IMPDH2; C5orf13; RBM42; ULK3; ZNF148; CSRP2; CBLN3; POU2F3; RYR1B; GOLPH3L

    DYNLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNLRB1.

    DYNC1LI2; RANGAP1; DYNLT3; ACTR1A; Ywhae; DYNC1I2; DCTN2; DCTN1; DYNC1H1; UBR2; CCDC82; WDR60; WDR34; LUC7L; DYNC1LI1

    Asante, D; Stevenson, NL; et al. Subunit composition of the human cytoplasmic dynein-2 complex. JOURNAL OF CELL SCIENCE 127:4774-4787(2014).
    Pagaev, RM; Kakuev, DL; et al. The light chain of the dynein complex DYNLRB1 interacts with NDP-kinase a from bovine retina. DOKLADY BIOCHEMISTRY AND BIOPHYSICS 447:286-288(2012).

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