DYNLRB1
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Official Full Name
dynein, light chain, roadblock-type 1 -
Overview
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. -
Synonyms
km23;Dncl2a
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
- SUMO
Involved Pathway
DYNLRB1 involved in several pathways and played different roles in them. We selected most pathways DYNLRB1 participated on our site, such as Assembly of the primary cilium,Intraflagellar transport,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organelle biogenesis and maintenance | MRPL37,GFM1,BBS4,TTC30A2,TTC30A,TNPO1,TFB2M,IFT88,GADD45GIP1,DYF-1 |
| Intraflagellar transport | TTC30A1,IFT81,KIF3C,DYNLRB2,IFT74,TNPO1,IFT27,DYNLL2B,TTC30B,KIF3B |
| Assembly of the primary cilium | CDK5RAP2,IFT43,B9D2,PKD2,HSPB11,TTC30A1,ARL13B,ARL3,CEP135,RPGRIP1L |
Protein Function
DYNLRB1 has several biochemical functions, for example, identical protein binding,motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNLRB1 itself. We selected most functions DYNLRB1 had, and list some proteins which have the same functions with DYNLRB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| motor activity | MYL6B,MYH8,MYH4,KIF1C,MYHZ1.1,DYNLL2,MYO7AA,MYO10,VMHCL,SMYHC1 |
| identical protein binding | SF1,LRP6,MCM6,DCTPP1,GRB2,SMAD1,CLDN16,VCP,PPP1R13L,SCUBE1 |
| protein binding | GLI3,KCTD14,SLC22A7,AEN,MAGEB4,G3BP1,ASS1,BDKRB1,C9orf78,Tnfrsf22 |
Interacting Protein
DYNLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNLRB1.
DYNC1LI2;RANGAP1;DYNLT3;ACTR1A;Ywhae;DYNC1I2;DCTN2;DCTN1;DYNC1H1;UBR2;CCDC82;WDR60;WDR34;LUC7L;DYNC1LI1
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References
- Asante, D; Stevenson, NL; et al. Subunit composition of the human cytoplasmic dynein-2 complex. JOURNAL OF CELL SCIENCE 127:4774-4787(2014).
- Pagaev, RM; Kakuev, DL; et al. The light chain of the dynein complex DYNLRB1 interacts with NDP-kinase a from bovine retina. DOKLADY BIOCHEMISTRY AND BIOPHYSICS 447:286-288(2012).
