EEA1 Protein, early endosome antigen 1


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Official Full Name early endosome antigen 1
Background Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Synonyms EEA1; early endosome antigen 1; MST105; ZFYVE2; MSTP105; early endosome antigen 1, 162kD; endosome-associated protein p162; early endosome-associated protein; zinc finger FYVE domain-containing protein 2;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EEA1-26H Recombinant Human EEA1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EEA1-28464TH Recombinant Human EEA1 Wheat Germ N/A
    Human EEA1-3902H Recombinant Human EEA1 protein, His-tagged E.coli His
    Mouse EEA1-4996M Recombinant Mouse EEA1 Protein Mammalian Cell His

    EEA1 involved in several pathways and played different roles in them. We selected most pathways EEA1 participated on our site, such as Endocytosis, Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis RAB11FIP4; RLN1; ZFYVE27; FLT1; CHMP6; LDLR; ADRB2B; NEDD4L; EPS15L1; ARFGEF2
    Phagosome FCAR; MPO; ITGB1A; DYNC1I1; ITGB5; ATP6V1AA; TLR2-1; C3A.1; RILP; ATP6V0A1
    Tuberculosis TGFB2; IFNA1; IRAK4; TLR9; HLA-DRB5; CLEC7A; IL1B; IFNA12; CD74; MAPK10

    EEA1 has several biochemical functions, for example, 1-phosphatidylinositol binding, GTP-dependent protein binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEA1 itself. We selected most functions EEA1 had, and list some proteins which have the same functions with EEA1. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol binding PLEKHA4; CCDC167; PLEKHA3; SCARB1; PLEKHA2; SNX9; EPB41; EEA1; ZFYVE1; SNX10
    GTP-dependent protein binding CDC42; MRAS; RAPGEF6; RAB5B; RAB38; RAPGEF5; GCHFR; HPS6; RASGRP4; GCH1
    calmodulin binding GM101; MYO5B; KCNN1A; TJP1; UPF3B; USP6; MYH10; PNCK; PHKA2; CAMSAP1L1
    protein binding ADAM33; GTF2H2C; DHRS1; TMEM171; Reln; SERP1; ALAS1; CDK1; EXOSC3; ATM
    protein homodimerization activity PDCD6; CITED1; PON1; CEBPE; IKBKG; EEA1; GHR; ACHE; KCNN2; LRRFIP1
    zinc ion binding MYLIPA; ZNF184; PDLIM3; PHF15; GATAD1; RLIM; RNF115; Adam6; TRIM38; ISL1L

    EEA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEA1.

    RAB5A; Stx6; ERBB2; RAB5B; SAMD9; Samd9l

    Rush, JS; Ceresa, BP; et al. RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms. MOLECULAR AND CELLULAR ENDOCRINOLOGY 381:188-197(2013).
    Sandgren, KJ; Smed-Sorensen, A; et al. Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation. JOURNAL OF IMMUNOLOGY 191:60-69(2013).

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