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EIF2S3

  • Official Full Name

    eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa

  • Overview

    The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]
  • Synonyms

    EIF2S3; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; EIF2; EIF2G; eIF-2gA; EIF2gamma; eukaryotic translation initiation factor 2 subunit 3; eIF-2gX; eIF-2-gamma X; eukaryotic translation initiation factor 2G; eukaryotic translation initiation factor 2 subunit gamma X;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF2S3-28379TH Recombinant Human EIF2S3 Wheat Germ N/A 90 amino acids
Human EIF2S3-3175H Recombinant Human EIF2S3 Protein, GST-tagged Wheat Germ GST
Human EIF2S3-4198HF Recombinant Full Length Human EIF2S3 Protein, GST-tagged In Vitro Cell Free System GST 472 amino acids
Zebrafish EIF2S3-11986Z Recombinant Zebrafish EIF2S3 Mammalian Cell His
Chicken EIF2S3-1407C Recombinant Chicken EIF2S3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF2S3 Related Articles

EIF2S3 involved in several pathways and played different roles in them. We selected most pathways EIF2S3 participated on our site, such as ABC-family proteins mediated transport, Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2S3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ABC-family proteins mediated transportABCB8;ABCA8;ABCE1;ABCC9;KCNJ11;APOA1B;ABCD3B;ABCA4A;ABCF1
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SEIF2S1;EIF4EB;EIF3K;EIF4A2;EIF1AXA;EIF2S1A;EIF4E;EIF4G1;EIF4A1
Cap-dependent Translation InitiationEIF4G1;EIF5;RPL35;EIF3K;EIF4H;EIF4A2;EIF4A1;EIF4EB;EIF4EBP1
Eukaryotic Translation InitiationEIF2B1;EIF1AX;EIF4EB;EIF4A1;EIF2S1;EIF4A2;EIF2S3;EIF4B;EIF3K
Formation of the ternary complex, and subsequently, the 43S complexEIF2S1;EIF1AX;EIF3K;EIF1AXA;EIF2S1A;EIF2S3;FAUB
GTP hydrolysis and joining of the 60S ribosomal subunitEIF4H;EIF3K;EIF2S1;EIF2S3;EIF2S1A;EIF1AXA;EIF4A1;EIF1AX;EIF4A2
Gene ExpressionZNF234;GM3258;IGF2BP3;USP9;MADD;ZNF324;POP7;EIF3K;PRPF8
L13a-mediated translational silencing of Ceruloplasmin expressionFAUB;EIF2S3;EIF4H;EIF1AX;EIF1AXA;EIF3K;EIF2S1A

EIF2S3 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2S3 itself. We selected most functions EIF2S3 had, and list some proteins which have the same functions with EIF2S3. You can find most of the proteins on our site.

Function Related Protein
GTP bindingDIRAS2;GNA13B;RASEF;RALB;ERAL1;FPGT;ARL8;GNA15.1;RHOAE
GTPase activityGNAV1;MRAS;GTPBP10;RAB43;TUBA1L;MXC;GTPBP1L;MXG;GFM2
protein bindingDPEP1;EIF6;SYCE2;RAP1GAP;AGO3;BMP1A;FBXL5;CCDC53;ZNF239
translation factor activity, RNA bindingEIF4H;PPP1R2P9;EEF1D;EIF2S2;CPEB1;CPEB1A;EIF2S3;EIF4G3;SOX11
translation initiation factor activityGTPBP1;EIF5B;MCTS1;EIF3F;EIF3J;EIF1AX;EIF2S1A;EIF2A;EIF4E2

EIF2S3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2S3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2S3.

EIF2S1; EIF2S2; EIF1B; GH1; HLA-B; CASP4; IKBKE; NDRG1; PRKAB1; TRAF6; yopM; ychF; ssrna_ug

Chang, YT; Yao, CT; et al. Verification of gene expression profiles for colorectal cancer using 12 internet public microarray datasets. WORLD JOURNAL OF GASTROENTEROLOGY 20:17476-17482(2014).
Chang, YT; Huang, CS; et al. Gene expression profile of peripheral blood in colorectal cancer. WORLD JOURNAL OF GASTROENTEROLOGY 20:14463-14471(2014).
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