epha10
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  • Official Full Name
  • EPH receptor A10
  • Background
  • Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important;mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells;(Aasheim et al., 2005 (PubMed 15777695)). See MIM 179610 for additional background on Eph receptors and;ephrins.
  • Synonyms
  • EPHA10; EPH receptor A10; ephrin type-A receptor 10; FLJ16103; FLJ33655; EphA10s protein; MGC43817
Cat.#:EPHA10-3376HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPHA10 Protein, GST-tagged
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Cat.#:EPHA10-1136HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPHA10 protein, His & T7-tagged
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Cat.#:EPHA10-369HTag:DDK|His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human EPHA10 Protein, DDK/His-tagged
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Cat.#:EPHA10-674HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human EPHA10, Fc Chimera
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Cat.#:EPHA10-567HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human EPHA10 cell lysate
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Involved Pathway

EPHA10 involved in several pathways and played different roles in them. We selected most pathways EPHA10 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHA10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
NFATC4; ABLIM1; HBEGF; SEMA3B; CSF2RB; CDK5R1B; SEMA4A; ITGB1B.1; RASA1; RHOB
Developmental Biology
NRG3; EFNA2A; PSPN; CACNG2B; CDK19; SREBF2; MYL12B; SPAG9; RHOC; CHL1
EPH-Ephrin signaling
EPHA4A; ARPC4; ARPC5; EFNB1; ARHGEF28; EPHA2; AP2M1; EFNA2; KDR; EPHB3A
EPH-ephrin mediated repulsion of cells
EFNB3B; EPHB4B; EFNA2A; AP2B1; EFNB1; EFNB2; EPHA2; EPHB4A; EFNA2; EPHA2A
EPHA-mediated growth cone collapse
EPHA2; SHB; EFNA4; EFNA1A; EPHA2A; EPHA4A; EFNA2; EPHA10; EFNA1; EFNA3B

Protein Function

EPHA10 has several biochemical functions, for example, ATP binding, ephrin receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHA10 itself. We selected most functions EPHA10 had, and list some proteins which have the same functions with EPHA10. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CHD6; UBE2E3; CHEK1; CDC6; ACSM5; ABCC12; GCLC; CMPK1; CCT8L2; PFKMA
Function ephrin receptor activity
Related Protein EPHB6; EPHA2A; EPHB4; EPHA2; EPHB3A; EPHA4B; EPHB3; EPHA5; EPHB2B; EPHA4A
Function protein binding
Related Protein NRIP2; ARPC3; TNFAIP1; ALDH3B1; GATA5; THOC7; CWC22; CDC5L; TNNI3K; UBE2D2
Function transmembrane-ephrin receptor activity
Related Protein EPHA1; EPHA10; EPHA4; EPHB2; EFNB3; EFNA3; EPHB1; EFNA4; EPHA5

EPHA10 Related Articles

Kamada, H; Taki, S; et al. Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD3. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 456:908-912(2015).
Allonby, O; El Zawily, AM; et al. Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction. CELLULAR SIGNALLING 26:2645-2657(2014).