epha7
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  • Official Full Name
  • Eph receptor A7
  • Background
  • This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically h
  • Synonyms
  • EPHA7; Eph receptor A7; ephrin type-A receptor 7; Cek 11; Developmental kinase 1; EBK; EHK-3; EHK3; EK11; Embryonic brain kinase; EPH homology kinase 3; EPH-like kinase 11; EPHA7_HUMAN; Ephrin receptor Eph A7; Ephrin type A receptor 7; hEK11; MDK 1; Receptor protein tyrosine kinase HEK 11; Tyrosine protein kinase receptor EHK 3; mDK-1; OTTMUSP00000005091; OTTMUSP00000005092; OTTMUSP00000005093; OTTMUSP00000005094; Mdk1; Cek11
Cat.#:EPHA7-1899HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPHA7 Protein, MYC/DDK-tagged
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Cat.#:EPHA7-3393HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human EPHA7 Protein, GST-tagged
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Cat.#:EPHA7-3394HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPHA7 Protein, GST-tagged
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Cat.#:EPHA7-697HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human EPH Receptor A7, GST-tagged
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Cat.#:EPHA7-12490HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPHA7, GST-tagged
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Cat.#:EPHA7-26442THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human EPHA7
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Cat.#:EPHA7-3228HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPHA7, His tagged
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Cat.#:EPHA7-369HTag:DDK|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPHA7 Protein, DDK/His-tagged
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Cat.#:EPHA7-370HTag:DDK
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human EPHA7 Protein, DDK-tagged
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Cat.#:EPHA7-551HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human EPHA7 Protein, Fc Chimera
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Cat.#:EPHA7-581HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human EPHA7
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Cat.#:EPHA7-7326HTag:His|GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human EPHA7, His & GST-tagged
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Cat.#:Epha7-542MTag:Fc Chimera
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Epha7, Fc Chimera
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Cat.#:Epha7-915MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Epha7, His tagged
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Cat.#:Epha7-1079RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epha7 Protein, Fc-tagged
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Cat.#:EPHA7-2121RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EPHA7 Protein
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Cat.#:EPHA7-433RTag:Fc|His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Epha7, His tagged
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Cat.#:EPHA7-6640CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EPHA7
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Cat.#:EPHA7-4067ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EPHA7
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Cat.#:EPHA7-745HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human EPH Receptor A7, GST-His
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Cat.#:Epha7-1013HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Eph Receptor A7, GST-tagged
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Cat.#:EPHA7-2236HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPHA7 cell lysate
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Cat.#:EPHA7-414HCLTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human EPHA7 cell lysate
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Cat.#:EPHA7-2125MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse EPHA7 cell lysate
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Cat.#:EPHA7-1100RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat EPHA7 cell lysate
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Cat.#:Kit-1554Tag:N/A
Source (Host):Species:
Product nameU2OS EphA7 Bioassay Kit
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Cat.#:Kit-1581Tag:N/A
Source (Host):Species:
Product nameEphA7 Functional Assay Kit
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Involved Pathway

EPHA7 involved in several pathways and played different roles in them. We selected most pathways EPHA7 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHA7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
NRP2; EFNB1; SCN3B; KDR; TRPC3; IL17RD; RGMB; L1CAM; CSF2RB; EFNB2

Protein Function

EPHA7 has several biochemical functions, for example, ATP binding, GPI-linked ephrin receptor activity, axon guidance receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHA7 itself. We selected most functions EPHA7 had, and list some proteins which have the same functions with EPHA7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein VARS2; PGS1; CSNK1A1L; KIF2C; ADRBK1; NLRC4; TYK2; CHD7; STK38L; UBE2E1
Function GPI-linked ephrin receptor activity
Related Protein EPHA8; EPHA4; EK1; EPHA7; EPHA5; EPHA3
Function axon guidance receptor activity
Related Protein ROBO2; EPHA7; ROBO1; EPHB1; GFRA3; SEMA5A; EPHB3
Function chemorepellent activity
Related Protein NRG1; SEMA4BA; SEMA3GB; SEMA3C; SEMA3GA; EFNA5; NRG3; SEMA3B; Sema3f; SEMA3AA
Function ephrin receptor binding
Related Protein EFNB1; CHN1; EFNA2A; EFNB2; EFNB3; EFNA5; EFNA3; EFNB2B; EPHA7; EFNA3B
Function protein binding
Related Protein VEGFA; PKM2; UBR2; VGLL2; ZNF202; XIAP; GSK3B; CDKN2C; RCN1; SPEG
Function protein tyrosine kinase activity
Related Protein ZNF143B; MAP3K11; KITB; EPHA2A; MAP2K4; ABL1; BMX; DYRK1B; TTN; KDRL

Interacting Protein

EPHA7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHA7 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHA7.
Efna1; EPHA2; ephopt; EPHA3; EFNA4; EFNA5; abl-tide; MLLT4; GNB1; ZNF267; MAP1LC3A; czc8004; linkable pd173955 analogue; bisindolylmaleimide iii; purvalanol b

EPHA7 Related Articles

Xue, CY; Chen, YQ; et al. EphB4 expression in pterygium is associated with microvessel density. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 7:4008-4015(2014).
Oricchio, E; Wendel, HG; et al. Functional genomics lead to new therapies in follicular lymphoma. BLAVATNIK AWARDS FOR YOUNG SCIENTISTS 2012 1293:18-24(2013).