epha8
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  • Official Full Name
  • EPH receptor A8
  • Background
  • This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily ty
  • Synonyms
  • EPHA8; EPH receptor A8; EEK, EphA8; ephrin type-A receptor 8; Hek3; EPH-like kinase 3; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; tyrosine-protein kinase
Cat.#:EPHA8-3396HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human EPHA8 Protein, GST-tagged
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Cat.#:EPHA8-346HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human EPHA8
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Cat.#:EPHA8-371HTag:DDK/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human EPHA8 Protein, DDK/His-tagged
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Cat.#:EPHA8-698HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human EPH Receptor A8, GST-tagged
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Cat.#:EPHA8-6999HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human EPHA8, GST-tagged
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Cat.#:EPHA8-727HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human EPHA8 Protein, Fc Chimera
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Cat.#:EPHA8-5247MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EPHA8 Protein
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Cat.#:Epha8-920MTag:Fc
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Epha8 Protein, Fc Chimera
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Cat.#:EPHA8-2145HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human EPH Receptor A8, His-tagged
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Cat.#:Epha8-1726MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Eph Receptor A8
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Involved Pathway

EPHA8 involved in several pathways and played different roles in them. We selected most pathways EPHA8 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHA8 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
CXCR4; NFATC4; SLC14A2; NFATC3; COL6A1; TRPC4; RGMB; KIF4A; Sema3f; CLTC

Protein Function

EPHA8 has several biochemical functions, for example, ATP binding, GPI-linked ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHA8 itself. We selected most functions EPHA8 had, and list some proteins which have the same functions with EPHA8. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein OBSCN; PIF1; HSPA7; CDK15; NMNAT2; TTN; PANK2; TNK2; THRAP3; UBE2Z
Function GPI-linked ephrin receptor activity
Related Protein EK1; EPHA4; EPHA8; EPHA7; EPHA5; EPHA3

EPHA8 Related Articles

Yan, Y; Wang, Q; et al. miR-10a controls glioma migration and invasion through regulating epithelial-mesenchymal transition via EphA8. FEBS LETTERS 589:756-765(2015).
McKinney, N; Yuan, LP; et al. EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. JOURNAL OF NEURO-ONCOLOGY 121:109-118(2015).