EPHB6
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Official Full Name
EPH receptor B6
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Overview
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands. -
Synonyms
EPHB6; EPH receptor B6; ephrin type-B receptor 6; HEP; tyrosine-protein kinase-defective receptor EPH-6; MGC129910; MGC129911;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- HEK293
- Human Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- DDK|His
- Fc
- GST
- hFc
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
EPHB6 involved in several pathways and played different roles in them. We selected most pathways EPHB6 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | RHOB;SPRED1;PLXNC1;Ntng2;EFNA1;SEMA3A;TRPC4;KLB;PPP3R2 |
EPHB6 has several biochemical functions, for example, ATP binding, ephrin receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHB6 itself. We selected most functions EPHB6 had, and list some proteins which have the same functions with EPHB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | NLRP10;AK4;TCP1;TNK2B;CCT4;MYO7B;UCK2A;PSMC4;MAP3K8 |
| ephrin receptor activity | EPHA10;EPHA2;EPHB4B;EPHB3;EK1;EPHB4A;EPHB2B;EPHB3A;EPHA4B |
| protein binding | STARD3;CYC1;Txn1;NDE1;ANKS4B;SESN2;ATE1;CYTH3;NPRL2 |
| receptor activity | PAQR3A;IL10RB;GRIK3;ITGB1A;NRXN3;KLRG1;MRC1;CADM1;GFRA1A |
EPHB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHB6.
HSP90AB1; SMAD2; SAT1; MLLT4; pepQ; hflX; BCL6
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