EPHX1

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EPHX1

Official Full Name epoxide hydrolase 1, microsomal (xenobiotic)
Background Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms EPHX1; epoxide hydrolase 1, microsomal (xenobiotic); EPHX; epoxide hydrolase 1; epoxide hydratase; MEH; EPOX; HYL1
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EPHX1-5311H Recombinant Human EPHX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human EPHX1-6065H Recombinant Human EPHX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Ephx1-959M Recombinant Mouse Ephx1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human EPHX1-205H Recombinant Human EPHX1 Mammalian Cell His
    Human EPHX1-22H Recombinant Human EPHX1 Protein, His-tagged Insect cell His
    Human EPHX1-28685TH Recombinant Human EPHX1 Wheat Germ N/A
    Human EPHX1-3407H Recombinant Human EPHX1 Protein, GST-tagged Wheat Germ GST
    Human EPHX1-390H Recombinant Human EPHX1, MYC/DDK-tagged HEK293 N/A
    Human EPHX1-463H Recombinant Human epoxide hydrolase 1, microsomal (xenobiotic), T7 tagged E.coli T7
    Human EPHX1-5064H Recombinant Human EPHX1, T7-tagged E.coli T7
    Human EPHX1-6586HCL Recombinant Human EPHX1 293 Cell Lysate HEK293 N/A
    Mouse EPHX1-5252M Recombinant Mouse EPHX1 Protein Mammalian Cell His
    Rhesus Macaque EPHX1-1486R Recombinant Rhesus monkey EPHX1 Protein, His-tagged Mammalian Cell His
    Zebrafish EPHX1-11294Z Recombinant Zebrafish EPHX1 Mammalian Cell His

    EPHX1 involved in several pathways and played different roles in them. We selected most pathways EPHX1 participated on our site, such as Metabolism of xenobiotics by cytochrome P, Bile secretion, Chemical carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of xenobiotics by cytochrome P UGT1A4; ALDH3B1; GSTM; AKR7A3; GSTM6; UGT1A2; UGT1A3; GSTT1; SULT2A1; HSD11B1
    Bile secretion SULT2A1; SLC22A8; SLC2A1; SLC51A; BAAT; SCARB1; ABCC3; CFTR; FXYD2; AQP8
    Chemical carcinogenesis HSD11B1; CYP2C38; NAT1; EPHX1; UGT2B15; GSTA1; ALDH1A3; CYP2A13; MGST1; SULT1A2

    EPHX1 has several biochemical functions, for example, cis-stilbene-oxide hydrolase activity, epoxide hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHX1 itself. We selected most functions EPHX1 had, and list some proteins which have the same functions with EPHX1. You can find most of the proteins on our site.

    Function Related Protein
    cis-stilbene-oxide hydrolase activity EPHX1
    epoxide hydrolase activity Npepo; RNPEP; EPHX4; EPHX1; LTA4H; EPHX3; EPHX2

    EPHX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHX1.

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