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Official Full Name EPS8-like 2
Background This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling.
Synonyms EPS8L2; EPS8-like 2; epidermal growth factor receptor kinase substrate 8-like protein 2; FLJ21935; FLJ22171; MGC3088; EPS8-like protein 2; EPS8-related protein 2; epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8R2; FLJ16738; MG
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Eps8l2-2848M Recombinant Mouse Eps8l2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human EPS8L2-5700H Recombinant Human EPS8L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human EPS8L2-12507H Recombinant Human EPS8L2, His-tagged E.coli His
    Human EPS8L2-2122H Recombinant Human EPS8L2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EPS8L2-28683TH Recombinant Human EPS8L2, His-tagged E.coli His
    Human EPS8L2-3429H Recombinant Human EPS8L2 Protein, GST-tagged Wheat Germ GST
    Human EPS8L2-571HCL Recombinant Human EPS8L2 cell lysate N/A
    Mouse EPS8L2-5268M Recombinant Mouse EPS8L2 Protein Mammalian Cell His

    EPS8L2 involved in several pathways and played different roles in them. We selected most pathways EPS8L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EPS8L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    EPS8L2 has several biochemical functions, for example, contributes_to Rac guanyl-nucleotide exchange factor activity, contributes_to Rho guanyl-nucleotide exchange factor activity, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPS8L2 itself. We selected most functions EPS8L2 had, and list some proteins which have the same functions with EPS8L2. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to Rac guanyl-nucleotide exchange factor activity EPS8L2; EPS8L1
    contributes_to Rho guanyl-nucleotide exchange factor activity EPS8L2; EPS8L1
    actin binding MTSS1LA; GSNB; LMOD1; MAEA; PDLIM5; GIPC1; FLNC; TBC1D21; FSCN2; ACTN3

    EPS8L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPS8L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPS8L2.

    LRRK2; CD3E; RPL23; PTK2; TNS2; RIN3; pi3p; SNW1; CDC5L

    Furness, DN; Johnson, SL; et al. Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:13898-13903(2013).
    Colas, E; Perez, C; et al. Molecular markers of endometrial carcinoma detected in uterine aspirates. INTERNATIONAL JOURNAL OF CANCER 129:2435-2444(2011).

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