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ESCO1

Official Full Name

establishment of cohesion 1 homolog 1 (S. cerevisiae)
Overview

ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005;(PubMed 15958495)).
Synonyms

ESCO1; establishment of cohesion 1 homolog 1 (S. cerevisiae); N-acetyltransferase ESCO1; EFO1; ESO1; KIAA1911; EFO1p; hEFO1; CTF7 homolog 1; ECO1 homolog 1; ESO1 homolog 1; establishment factor-like protein 1; CTF; ECO1; A930014I12Rik;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ESCO1-3496H	Recombinant Human ESCO1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ESCO1-572HCL	Recombinant Human ESCO1 cell lysate		N/A		Inquiry
Human	ESCO1-4698HF	Recombinant Full Length Human ESCO1 Protein, GST-tagged	In Vitro Cell Free System	GST	172 amino acids	Inquiry
Mouse	ESCO1-5318M	Recombinant Mouse ESCO1 Protein	Mammalian Cell	His		Inquiry
Mouse	ESCO1-2861M-B	Recombinant Mouse ESCO1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ESCO1-2861M	Recombinant Mouse ESCO1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ESCO1 Related Articles

ESCO1 involved in several pathways and played different roles in them. We selected most pathways ESCO1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Establishment of Sister Chromatid Cohesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESCO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	PMF1;CTDNEP1;SMC1AL;YWHABA;MAPRE1A;CCND3;MPEG1.1;ENSAB;TEX15
Cell Cycle, Mitotic	MAPRE1;CCDC99;ITGB3BP;TUBG2;NEDD1;KIF18A;PDS5A;ODF2B;CEP70
Establishment of Sister Chromatid Cohesion	STAG2;PDS5A;CDCA5;STAG1;WAPAL;ESCO1;PDS5B;ESCO2
S Phase	ESCO2;ESCO1;GINS1;MYCA;GINS4;GINS2;GINS3

ESCO1 has several biochemical functions, for example, metal ion binding, transferase activity, transferring acyl groups. Some of the functions are cooperated with other proteins, some of the functions could acted by ESCO1 itself. We selected most functions ESCO1 had, and list some proteins which have the same functions with ESCO1. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	MB;DNAJA4;CYP2P8;USP4;ZNF362B;CLCNKA;ZNF609A;TUT1;CXXC1B
transferase activity, transferring acyl groups	AANAT1;ACNAT2;CHAC2;SPTLC3;ZDHHC18;PIGW;TMEM68;NAT15;MEIS2

ESCO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESCO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ESCO1.

Esco1

Carretero, M; Ruiz-Torres, M; et al. Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres. EMBO JOURNAL 32:2938-2949(2013).

Price, JC; Pollock, LM; et al. Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A. PLOS ONE 8:-(2013).