exosc5
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  • Official Full Name
  • exosome component 5
  • Background
  • Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex.
  • Synonyms
  • EXOSC5; exosome component 5; exosome complex component RRP46; exosome component Rrp46; hRrp46p; MGC12901; p12B; RRP41B; RRP46; Rrp46p; Chronic myelogenous leukemia tumor antigen 28; Ribosomal RNA processing protein 46; CML28; EXOSC 5; exosome complex exonuclease RRP46; ribosomal RNA-processing protein 46
Cat.#:EXOSC5-3575HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EXOSC5 Protein, GST-tagged
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Cat.#:EXOSC5-12598HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EXOSC5, His-tagged
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Cat.#:EXOSC5-28337THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EXOSC5, His-tagged
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Cat.#:EXOSC5-5385MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EXOSC5 Protein
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Cat.#:EXOSC5-4330ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EXOSC5
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Cat.#:EXOSC5-6500HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EXOSC5 293 Cell Lysate
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Involved Pathway

EXOSC5 involved in several pathways and played different roles in them. We selected most pathways EXOSC5 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOSC5 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA degradation
WDR61; XRN2; TOB1A; LSM5; LSM8; BTG4; PATL1; PABPC1A; CNOT6L; RQCD1

Protein Function

EXOSC5 has several biochemical functions, for example, 3-5-exoribonuclease activity, RNA binding, NOT exoribonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOSC5 itself. We selected most functions EXOSC5 had, and list some proteins which have the same functions with EXOSC5. You can find most of the proteins on our site.
Function
Related Protein
Function 3-5-exoribonuclease activity
Related Protein EXOSC7; EXOSC3; PAN2; ERI2; CNOT8; EXOSC4; DOM3Z; EXOSC2; EXOSC5; ERI1
Function RNA binding
Related Protein FBL; EXOSC7; XPO1; RPL18A; FAM120A; EIF4E1B; EIF3B; RNASEL4; MPHOSPH6; NHP2L1A
Function NOT exoribonuclease activity
Related Protein EXOSC3; EXOSC8; EXOSC1; EXOSC4; EXOSC2; EXOSC7; EXOSC5
Function protein binding
Related Protein TGFB1I1; SKP1; LAPTM5; ATP1A2; PRSS2; DCTPP1; BMPR1A; SILV; PKMYT1; C8orf33

Interacting Protein

EXOSC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOSC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOSC5.
EXOSC1; EXOSC8