Recombinant Human EXOSC5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EXOSC5-1027H
• Product Overview: EXOSC5 MS Standard C13 and N15-labeled recombinant protein (NP_064543) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: EXOSC5 (Exosome Component 5) is a Protein Coding gene. Diseases associated with EXOSC5 include Cat-Scratch Disease and Pontocerebellar Hypoplasia, Type 1B. Among its related pathways are rRNA processing in the nucleus and cytosol and Regulation of activated PAK-2p34 by proteasome mediated degradation. Gene Ontology (GO) annotations related to this gene include RNA binding and exoribonuclease activity. An important paralog of this gene is EXOSC6.
• Molecular Mass: 25.3 kDa
• AA Sequence: MEEEMHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EXOSC5 exosome component 5 [ Homo sapiens (human) ]
• Official Symbol: EXOSC5
• Synonyms: EXOSC5; exosome component 5; exosome complex component RRP46; exosome component Rrp46; hRrp46p; MGC12901; p12B; RRP41B; RRP46; Rrp46p; exosome complex exonuclease RRP46; ribosomal RNA-processing protein 46; chronic myelogenous leukemia tumor antigen 28; MGC111224
• Gene ID: 56915
• mRNA Refseq: NM_020158
• Protein Refseq: NP_064543
• MIM: 606492
• UniProt ID: Q9NQT4