ece2
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  • Official Full Name
  • endothelin converting enzyme 2
  • Background
  • Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally;pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 (PubMed 11718899)).
  • Synonyms
  • ECE2; endothelin converting enzyme 2; endothelin-converting enzyme 2; KIAA0604; MGC2408; MGC78487; ECE 2; ECE-2; ECE2_HUMAN; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; MGC17664
Cat.#:ECE2-3028HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ECE2 Protein, GST-tagged
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Cat.#:Ece2-222MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ece2 Protein, His-tagged
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Cat.#:ECE2-12265HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ECE2, His-tagged
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Cat.#:ECE2-3813HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ECE2, His tagged
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Cat.#:ECE2-529HTag:His/Val
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human ECE2, His&Val-tagged
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Cat.#:ECE2-690HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ECE2, Fc tagged
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Cat.#:ECE2-2052HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ECE2 cell lysate
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Cat.#:ECE2-2976HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human ECE2 cell lysate
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Protein Function

ECE2 has several biochemical functions, for example, metal ion binding, metalloendopeptidase activity, methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ECE2 itself. We selected most functions ECE2 had, and list some proteins which have the same functions with ECE2. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein SMAD4; TDO2; ZFP523; SMYD1A; ZDHHC8B; ZNF786; TRIM35-24; B4GALT2; PPP2CA; FAHD2B
Function metalloendopeptidase activity
Related Protein MMP30; C6AST4; MME; ADAM18; OSGEPL1; MMP25; MMEL1; MMP14A; ADAM10B; KEL
Function methyltransferase activity
Related Protein FAM86; METTL8; C20orf7; FAM86C; METTL4; GART; RNMTL1A; METTL21A; PRDM14; FTSJD1
Function protein binding
Related Protein FOXO3; ARMC9; PKN3; CHRM3; ABCB9; ATL2; ALOX15; EFHC2; ADAP1; IFRD2

Interacting Protein

ECE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ECE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ECE2.
SYNE4; NDUFS1; CD86; CASP10

ECE2 Related Articles

Maguire, JJ; Davenport, AP; et al. Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. BRITISH JOURNAL OF PHARMACOLOGY 171:5555-5572(2014).
Mouthon, L; Bussone, G; et al. Scleroderma Renal Crisis. JOURNAL OF RHEUMATOLOGY 41:1040-1048(2014).