Recombinant Human ECE2, His-tagged

• Cat.No.: ECE2-12265H
• Product Overview: Recombinant Human ECE2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-255a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ECE2 endothelin converting enzyme 2 [ Homo sapiens ]
• Official Symbol: ECE2
• Synonyms: ECE2; endothelin converting enzyme 2; endothelin-converting enzyme 2; KIAA0604; MGC2408; ECE-2; MGC17664; MGC78487
• Gene ID: 9718
• mRNA Refseq: NM_001037324
• Protein Refseq: NP_001032401
• MIM: 610145
• UniProt ID: O60344
• Chromosome Location: 3q27.1
• Function: metal ion binding; metalloendopeptidase activity; methyltransferase activity; peptidase activity; transferase activity