Epha4 Protein, EPH receptor A4


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Official Full Name EPH receptor A4
Background This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically h
Synonyms EPHA4; EPH receptor A4; EphA4 , TYRO1; ephrin type-A receptor 4; Hek8; EK8; EPH-like kinase 8; TYRO1 protein tyrosine kinase; tyrosine-protein kinase TYRO1; tyrosine-protein kinase receptor SEK; receptor protein-tyrosine kinase HEK8; SEK; TYRO1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • NSO
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • His
    • Fc
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EPHA4-001HCL Recombinant Human EPHA4 cell lysate Insect Cell N/A
    Human EPHA4-1137H Recombinant Human EPHA4 protein, His & GST-tagged E.coli His/GST
    Human EPHA4-1933HCL Recombinant Human EPHA4 cell lysate Human Cell N/A
    Human EPHA4-26439TH Recombinant Human EPHA4 N/A
    Human EPHA4-302H Recombinant Human EPH Receptor A4, GST-tagged, Active Sf9 Insect Cell GST
    Human EPHA4-3204H Recombinant Human EPHA4, His tagged Human Cell His
    Human EPHA4-3384H Recombinant Human EPHA4 Protein, GST-tagged Insect Cell GST
    Human EPHA4-3385H Recombinant Human EPHA4 Protein, GST/His-tagged Insect Cell GST/His
    Human EPHA4-3386H Recombinant Human EPHA4 Protein, GST-tagged Wheat Germ GST
    Human EPHA4-366H Recombinant Human EPHA4 Protein, DDK/His-tagged HEK293 DDK/His
    Human EPHA4-550H Recombinant Human EPHA4 Protein, Fc Chimera NS0 Fc
    Human EPHA4-7315H Recombinant Human EPHA4, His & GST tagged Insect Cell His/GST
    Human EPHA4-942H Recombinant Human EPHA4, Fc-His tagged Human Cell Fc/His
    Mouse Epha4-1724M Recombinant Mouse Eph Receptor A4 NSO N/A
    Mouse EPHA4-2136MCL Recombinant Mouse EPHA4 cell lysate Human Cell N/A
    Mouse Epha4-912M Recombinant Mouse Epha4, Fc tagged Human Cell Fc
    Mouse Epha4-913M Recombinant Mouse Epha4, His tagged Human Cell His
    Rat EPHA4-1446RCL Recombinant Rat EPHA4 cell lysate Human Cell N/A
    Rat Epha4-7439R Recombinant Rat Epha4, Fc tagged Human Cell Fc
    Rat Epha4-7440R Recombinant Rat Epha4, His tagged Human Cell His
    Cynomolgus Monkey EPHA4-1192CCL Recombinant Cynomolgus EPHA4 cell lysate Human Cell N/A
    Rhesus Macaque EPHA4-1175R Recombinant Rhesus EPHA4 Protein, Fc-tagged HEK293 Fc
    Rhesus Macaque EPHA4-1176R Recombinant Rhesus EPHA4 Protein, His-tagged HEK293 His
    Rhesus Macaque EPHA4-1484R Recombinant Rhesus monkey EPHA4 Protein, His-tagged Mammalian Cell His
    Chicken EPHA4-6345C Recombinant Chicken EPHA4 Mammalian Cell His

    Epha4 involved in several pathways and played different roles in them. We selected most pathways Epha4 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Epha4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance CAP2; CXCL12; NTN1A; EPHB4; AP2B1; DPYSL4; NCAN; ROBO2; CSNK2A1; DPYSL3

    Epha4 has several biochemical functions, for example, ATP binding, DH domain binding, GPI-linked ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Epha4 itself. We selected most functions Epha4 had, and list some proteins which have the same functions with Epha4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding TLK1A; CSNK1E; TTLL10; ABCG2D; POMK; MAP2K4; ALDH18A1; ILF2; STK4; STK24B
    DH domain binding EPHA4
    GPI-linked ephrin receptor activity EK1; EPHA4; EPHA5; EPHA7; EPHA3; EPHA8
    PH domain binding EPB41L2; INPP5A; EPHA4
    ephrin receptor binding ANKS1B; EFNA1A; SDCBP; EFNA2A; Anks1; NTRK1; EFNB2A; EFNA1B; EFNA3; EFNA5B
    identical protein binding TARDBP; ZNF703; RASSF3; IIGP1; RABAC1; SOX10; VIL1; APAF1; RNF4; ATG16L1
    protein binding WWP2; GNB3; ATXN7; STK40; KRT20; PARVA; HIST1H4C; DUSP14; KBTBD6; APBB1IP
    protein kinase activity LMTK3; CDC7; GSK3AB; GC3; SRPK1B; CAMK1DA; FASTKD5; PTK7A; PLK1; RPS6KA3B
    transmembrane-ephrin receptor activity EFNB3; EPHA5; EFNA3; EFNA4; EPHB1; EPHB2; EPHA4; EPHA1; EPHA10

    Epha4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Epha4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Epha4.


    Shi, M; Movius, J; et al. Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation. MOLECULAR & CELLULAR PROTEOMICS 14:544-555(2015).
    Kempf, A; Montani, L; et al. Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. EUROPEAN JOURNAL OF NEUROSCIENCE 38:3567-3579(2013).

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