F2RL2 Protein, coagulation factor II (thrombin) receptor-like 2

F2RL2

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F2RL2

Official Full Name coagulation factor II (thrombin) receptor-like 2
Background This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
Synonyms F2RL2; coagulation factor II (thrombin) receptor-like 2; PAR3; PAR-3; proteinase-activated receptor 3; thrombin receptor-like 2; protease-activated receptor 3; proteinase-activated receptor-3; Coagulation factor II receptor-like 2 (protease-actovated receptor 3);
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human F2RL2-3617H Recombinant Human F2RL2 Protein Wheat Germ N/A
    Mouse F2RL2-5411M Recombinant Mouse F2RL2 Protein Mammalian Cell His
    Rat F2RL2-2178R Recombinant Rat F2RL2 Protein Mammalian Cell His

    F2RL2 involved in several pathways and played different roles in them. We selected most pathways F2RL2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with F2RL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction LHBETA1; TACR1A; GALR1; PTAFR; NPY8AR; GALR2; PRL2; HRH1; CCKAR; CHRNB3B

    F2RL2 has several biochemical functions, for example, G-protein coupled receptor activity, signal transducer activity, thrombin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by F2RL2 itself. We selected most functions F2RL2 had, and list some proteins which have the same functions with F2RL2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity FPR2; VMN1R50; TAAR7A; VIPR1B; VMN1R41; TAAR12E; FZD3; TACR3A; ADCYAP1R1A; OR12D3
    signal transducer activity HTR1AB; CBLC; STAT1A; GNA14; OPN1LW1; HTR5AL; OPN1LW2; F2RL2; SH2B3; PRLH2R
    thrombin receptor activity F2RL1.1; GP1BA; F2RL1.2; F2R; F2RL2; F2RL1

    F2RL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F2RL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of F2RL2.

    Smad7; Smad1; Smad4; Smad2; SMAD3

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