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FAAH

  • Official Full Name

    fatty acid amide hydrolase

  • Overview

    This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide.
  • Synonyms

    FAAH; fatty acid amide hydrolase; fatty-acid amide hydrolase 1; FAAH 1; Anandamide amidohydrolase 1; Anandamide amidohydrolase; FA2H; FAAH-1; FAAH1_HUMAN; Fatty acid 2-hydroxylase; Fatty acid alpha-hydroxylase; MGC102823; MGC138146; Oleamide hydrolase 1; Oleamide hydrolase; OTTHUMP00000009480;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Arabidopsis thaliana (Mouse-ear cress)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Insect cell
  • Insect Cell
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FAAH-621H Recombinant Human FAAH Mammalian Cell His
Human FAAH-20H Recombinant Human FAAH, MYC/DDK-tagged HEK293 Myc/DDK
Human FAAH-26642TH Recombinant Human FAAH, GST-tagged Wheat Germ GST
Human FAAH-12629H Recombinant Human FAAH, GST-tagged E.coli GST 236-579a.a.
Human FAAH-19H Recombinant Human FAAH protein, His-tagged Insect Cell His
Human FAAH-057H Recombinant Human FAAH Protein, His-tagged Insect cell His
Human FAAH-2894H-B Recombinant Human FAAH Protein Pre-coupled Magnetic Beads HEK293
Human FAAH-7192HFL Recombinant Full Length Human FAAH, Flag-tagged Mamanlian cells Flag
Human FAAH-21R Recombinant Active Human FAAH Protein (30-579), N-His-tagged E.coli N-His 30-579
Human FAAH-2894H Recombinant Human FAAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Faah-1455M Recombinant Mouse Faah Protein, His&GST-tagged E.coli N-His&GST Asp57-Thr167
Mouse Faah-1002M Recombinant Mouse Faah Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat FAAH-2183R Recombinant Rat FAAH Protein Mammalian Cell His
Rat Faah-1456R Recombinant Rat Faah Protein, His&GST-tagged E.coli N-His&GST Asp57-Thr167
Rat FAAH524R Recombinant Rat FAAH (32-579) (L192F,F194Y,A377T,S435N,I491V,V495M) Protein
Rat FAAH-1840R Recombinant Rat FAAH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FAAH19685R Recombinant Rat FAAH (24-579) (mutations L192F,F194Y,A377T,S435N,I491V,V495M) Protein
Rat FAAH-1840R-B Recombinant Rat FAAH Protein Pre-coupled Magnetic Beads HEK293
Arabidopsis thaliana (Mouse-ear cress) RFL27044AF Recombinant Full Length Arabidopsis Thaliana Fatty Acid Amide Hydrolase(Faah) Protein, His-Tagged E.coli expression system His Full Length (1-607)
Homo sapiens (Human) RFL17615HF Recombinant Full Length Human Fatty-Acid Amide Hydrolase 1(Faah) Protein, His-Tagged E.coli expression system His Full Length (1-579)
Mus musculus (Mouse) RFL32082MF Recombinant Full Length Mouse Fatty-Acid Amide Hydrolase 1(Faah) Protein, His-Tagged E.coli expression system His Full Length (1-579)
Rattus norvegicus (Rat) RFL28695RF Recombinant Full Length Rat Fatty-Acid Amide Hydrolase 1(Faah) Protein, His-Tagged E.coli expression system His Full Length (1-579)
Zebrafish FAAH-6069Z Recombinant Zebrafish FAAH Mammalian Cell His
Kit-1953 FAAH Inhibitor Screening Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FAAH Related Articles

FAAH involved in several pathways and played different roles in them. We selected most pathways FAAH participated on our site, such as Retrograde endocannabinoid signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Retrograde endocannabinoid signalingGABRD;GNG10;GNG13;PRKACG;GABRB3;GABRA5;GNG7;GABRB1;PRKCB

FAAH has several biochemical functions, for example, acylglycerol lipase activity, carbon-nitrogen ligase activity, with glutamine as amido-N-donor, fatty acid amide hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FAAH itself. We selected most functions FAAH had, and list some proteins which have the same functions with FAAH. You can find most of the proteins on our site.

Function Related Protein
acylglycerol lipase activityABHD6;PNLIPRP2;ABHD12;FAAH;MGLL
carbon-nitrogen ligase activity, with glutamine as amido-N-donorFAAH2B;FAAH2A;FAAH2;PET112L;GATB;FAAH
fatty acid amide hydrolase activity
protein bindingNCOR1;TRIM33;MYL12A;SRPX2;UCN;CLNK;STAU2;MICAL1;UBE2K

FAAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAAH here. Most of them are supplied by our site. Hope this information will be useful for your research of FAAH.

NOTCH2NL; dinB; MME

Suarez, J; Romero-Zerbo, SY; et al. Endocannabinoid System in the Adult Rat Circumventricular Areas: An Immunohistochemical Study. JOURNAL OF COMPARATIVE NEUROLOGY 518:3065-3085(2010).
Straiker, A; Hu, SSJ; et al. Monoacylglycerol Lipase Limits the Duration of Endocannabinoid-Mediated Depolarization-Induced Suppression of Excitation in Autaptic Hippocampal Neurons. MOLECULAR PHARMACOLOGY 76:1220-1227(2009).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
How does FAAH contribute to the metabolism of bioactive lipids and their physiological effects? 04/04/2022

FAAH is involved in the metabolism of bioactive lipids, affecting various physiological functions.

How does FAAH (Fatty Acid Amide Hydrolase) regulate the breakdown of endocannabinoids and fatty acid amides? 09/02/2021

FAAH breaks down endocannabinoids and fatty acid amides, regulating their levels and effects in the body.

How does FAAH influence mood and behaviors, particularly in relation to anxiety and depression? 05/19/2021

FAAH influences mood and behavior, playing a role in conditions like anxiety and depression.

What are the mechanisms by which FAAH modulates the endocannabinoid system and its related signaling pathways? 04/25/2021

FAAH regulates the endocannabinoid system, affecting neurotransmission and cellular signaling.

What is the impact of FAAH on appetite regulation and energy balance? 09/05/2020

FAAH impacts appetite and energy balance, potentially influencing eating behaviors and metabolic processes.

How do alterations in FAAH activity or expression affect the development and treatment of substance abuse disorders? 08/15/2018

Changes in FAAH activity can influence substance abuse disorders, impacting addiction and treatment responses.

What role does FAAH play in modulating pain perception and the body's response to stress? 07/14/2018

FAAH modulates pain and stress responses by controlling endocannabinoid signaling.

Customer Reviews (3)

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Reviews
08/18/2022

    Critical expertise in protein engineering, unmatched in quality and efficiency.

    04/03/2021

      Dependable peptide synthesis, accelerates our peptide-focused projects effectively.

      08/28/2019

        Efficient protein purification, delivers consistent yields and purity.

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