FAIM3 Protein, Fas apoptotic inhibitory molecule 3


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Official Full Name Fas apoptotic inhibitory molecule 3
Background Apoptosis is an important process in maintaining normal tissue homeostasis and function. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas associated death domain (FADD), containing death inducing signalling complex, and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7 (Curting and Cotter, 2003).
Synonyms Fas apoptotic inhibitory molecule 3; FAIM3; FCMR; TOSO; Fc mu receptor; IgM Fc receptor; OTTHUMP00000034619; OTTHUMP00000228559; immunoglobulin mu Fc receptor; regulator of Fas-induced apoptosis Toso
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • Human Cell
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse FAIM3-495M Recombinant Mouse FAIM3 Protein (18-262 aa), His-SUMO-tagged E.coli His/SUMO
    Human FAIM3-277H Recombinant Human FAIM3, Fc-tagged Human Cell Fc
    Human FAIM3-753HCL Recombinant Human FAIM3 cell lysate Human Cell N/A
    Mouse FAIM3-5441M Recombinant Mouse FAIM3 Protein Mammalian Cell His
    Rat FAIM3-2202R Recombinant Rat FAIM3 Protein Mammalian Cell His
    Rhesus Macaque FAIM3-1546R Recombinant Rhesus monkey FAIM3 Protein, His-tagged Mammalian Cell His

    FAIM3 involved in several pathways and played different roles in them. We selected most pathways FAIM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAIM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    FAIM3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FAIM3 itself. We selected most functions FAIM3 had, and list some proteins which have the same functions with FAIM3. You can find most of the proteins on our site.

    Function Related Protein

    FAIM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAIM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAIM3.


    Kubagawa, H; Kubagawa, Y; et al. The Old but New IgM Fc Receptor (Fc mu R). FC RECEPTORS 382:3-28(2014).
    Ding, ZJ; Bergman, A; et al. Complement-Activating IgM Enhances the Humoral but Not the T Cell Immune Response in Mice. PLOS ONE 8:-(2013).

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