Recombinant Mouse FAIM3 Protein (18-262 aa), His-SUMO-tagged

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Recombinant Mouse FAIM3 Protein (18-262 aa), His-SUMO-tagged

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Cat.No. : FAIM3-495M
Product Overview : Recombinant Mouse FAIM3 Protein (18-262 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Partial.
Description : May play a role in the immune syst processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Ses to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Source : E. coli
Species : Mouse
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 43.9 kDa
Protein length : 18-262 aa
AA Sequence : RVLPEVQLNV EWGGSIIIEC PLPQLHVRMY LCRQMAKPGI CSTVVSNTFV KKEYERRVTL TPCLDKKLFL VEMTQLTEND DGIYACGVGM KTDKGKTQKI TLNVHNEYPE PFWEDEWTSE RPRWLHRFLQ HQMPWLHGSE HPSSSGVIAK VTTPAPKTEA PPVHQPSSIT SVTQHPRVYR AFSVSATKSP ALLPATTASK TSTQQAIRPL EASYSHHTRL HEQRTRHHGP HYGREDRGLH IPIPE
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Faim3 Fas apoptotic inhibitory molecule 3 [ Mus musculus ]
Official Symbol : FAIM3
Synonyms : FAIM3; Toso; 1810037B05Rik; MGC144825; MGC144826;
Gene ID : 69169
mRNA Refseq : NM_026976
Protein Refseq : NP_081252
UniProt ID : A1KXC4

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