• Official Full Name
  • F-box protein 22
  • Background
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • FBXO22; F-box protein 22; F box only protein 22; F-box only protein 22; FBX22; FIST domain containing 1; FISTC1; F-box protein FBX22p44; FLJ13986; MGC31799
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO22 Protein, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO22, GST-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO22 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FBXO22 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FBXO22
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FBXO22
Source (Host):Species:Human
Product nameRecombinant Human FBXO22 293 Cell Lysate

Protein Function

FBXO22 has several biochemical functions, for example, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO22 itself. We selected most functions FBXO22 had, and list some proteins which have the same functions with FBXO22. You can find most of the proteins on our site.
Related Protein
Function ubiquitin-protein transferase activity
Related Protein TRIM23; UBR4; UBE2W; RNF10; UBE2G2; RNF146; CBL; TSPAN17; RNF144AB; ARIH1L

Interacting Protein

FBXO22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO22 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO22.
COPS6; COPS5; NCOR2; midostaurin; SKP1