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FBXO40

Official Full Name

F-box protein 40
Overview

Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
Synonyms

FBXO40; F-box protein 40; F-box only protein 40; Fbx40; KIAA1195; F box only protein 40; Muscle disease related protein; muscle disease-related protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Strep
Myc
DDK
N/A
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FBXO40-3946H	Recombinant Human FBXO40 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FBXO40-607HCL	Recombinant Human FBXO40 cell lysate		N/A		Inquiry
Human	FBXO40-1046H	Recombinant Human FBXO40 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	FBXO40-4677HF	Recombinant Full Length Human FBXO40 Protein, GST-tagged	In Vitro Cell Free System	GST	709 amino acids	Inquiry
Human	FBXO40-0870H	Recombinant Human FBXO40 Protein (G2-S709), Tag Free	Insect Cell	No tag	G2-S709	Inquiry
Human	FBXO40-0871H	Recombinant Human FBXO40 Protein (G2-S709), His/Strep tagged	Insect Cell	His/Strep	G2-S709	Inquiry
Mouse	FBXO40-5751M	Recombinant Mouse FBXO40 Protein	Mammalian Cell	His		Inquiry
Mouse	FBXO40-3167M-B	Recombinant Mouse FBXO40 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	FBXO40-3167M	Recombinant Mouse FBXO40 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Fbxo40-2970M	Recombinant Mouse Fbxo40 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
FBXO40 Related Articles

FBXO40 involved in several pathways and played different roles in them. We selected most pathways FBXO40 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO40 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FBXO40 has several biochemical functions, for example, molecular_function, ubiquitin protein ligase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO40 itself. We selected most functions FBXO40 had, and list some proteins which have the same functions with FBXO40. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	SNCGA;TMEM258;DPCR1;MUM1L1;SLAIN1;VMN1R95;SMC5;PSTPIP1B;NANOS1
ubiquitin protein ligase activity	SMURF2;HERC4;TRIM3;ITCHA;MARCH1;TRIM37;RNF121;RBBP6;MED17
zinc ion binding	TRIM36;LONRF3;RABGGTB;PHC2;VPS29;LIN28A;RBM4;CPO;KLF7

FBXO40 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO40 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO40.

HSP90AB1

Palus, S; von Haehling, S; et al. Muscle wasting: an overview of recent developments in basic research. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE 5:193-198(2014).

Kirk-Ballard, H; Kilroy, G; et al. An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin-proteasome system enzymes in skeletal muscle: Potential role in the treatment of sarcopenic obesity. NUTRITION 30:S21-S25(2014).