Recombinant Human FBXO40 Protein, GST-tagged

• Cat.No.: FBXO40-3946H
• Product Overview: Human FBXO40 full-length ORF ( NP_057382.1, 1 a.a. - 709 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 106.2 kDa
• AA Sequence: MGKARRSPPGHHRHCEGCFNRHCHI PVEPNTSCLVISCHLLCGATFHMCK EAEHQLLCPLEQVPCLNSEYGCPLS MSRHKLAKHLQVCPASVVCCSMEWN RWPNVDSETTLHENIMKETPSEECL DTALALQDQKVLFRSLKMVELFPET REATEEEPTMNGETSVEEMGGAVGG VDIGLVPHGLSATNGEMAELSQEER EVLAKTKEGMDLVKFGQWENIFSKE HAASALTNSSASCESKNKNDSEKEQ ISSGHNMVEGEGAPKKKEPQENQKQ QDVRTAMETTGLAPWQDGVLERLKT AVDAKDYNMYLVHNGRMLIHFGQMP ACTPKERDFVYGKLEAQEVKTVYTF KVPVSYCGKRARLGDAMLSCKPSEH KAVDTSDLGITVEDLPKSDLIKTTL QCALERELKGHVISESRSIDGLFMD FATQTYNFEPEQFSSGTVLADLTAA TPGGLHVELHSECVTRRHNKSSSAF TFTCNKFFRRDEFPLHFKNVHTDIQ SCLNGWFQHRCPLAYLGCTFVQNHF RPPGQKAKVIYSQELKTFAIKPEVA PELSEGRKNNHLLGHGGKSQNSLTS LPLEILKYIAGFLDSVSLAQLSQVS VLMRNICATLLQERGMVLLQWKKKR YSHGGTSWRVHREIWQFSSLFSKIK SWEFNEVTSMSEHLKSCPFNIVEHK TDPILLTSMCQPREQARESLVSTFR IRPRGRYVS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXO40 F-box protein 40 [ Homo sapiens ]
• Official Symbol: FBXO40
• Synonyms: FBXO40; F-box protein 40; F-box only protein 40; Fbx40; KIAA1195; muscle disease-related protein; FBX40; MGC129902; MGC129903
• Gene ID: 51725
• mRNA Refseq: NM_016298
• Protein Refseq: NP_057382
• MIM: 609107
• UniProt ID: Q9UH90