FGF6 Protein, fibroblast growth factor 6

FGF6

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FGF6

Official Full Name fibroblast growth factor 6
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
Synonyms FGF6; fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; OTTHUMP00000238378; heparin-binding growth factor 6; heparin secretory-transforming protein 2; HST2; HBGF-6
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF6-12872H Recombinant Human FGF6, GST-tagged E.coli GST
    Human FGF6-176H Recombinant Human Fibroblast Growth Factor 6 E.coli N/A
    Human FGF6-573H Recombinant Human FGF6 E.coli N/A
    Human FGF6-6237HCL Recombinant Human FGF6 293 Cell Lysate HEK293 N/A
    Human FGF6-644H Recombinant Human FGF6 protein, His & GST-tagged E.coli His/GST
    Mouse Fgf6-527M Recombinant Mouse Fibroblast Growth Factor 6 E.coli N/A
    Mouse FGF6-5855M Recombinant Mouse FGF6 Protein Mammalian Cell His
    Mouse Fgf6-637M Recombinant Mouse Fgf6 E.coli N/A
    Mouse Fgf6-645M Recombinant Mouse Fgf6 protein, His & T7-tagged E.coli His/T7
    Rat Fgf6-646R Recombinant Rat Fgf6 protein, His & GST-tagged E.coli His/GST

    FGF6 involved in several pathways and played different roles in them. We selected most pathways FGF6 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MAP4K2; RAP1A; CACNA1SA; PPP3R2; RAC1A; PLA2G4C; FGF11A; TP53; RAC2; FGF6B
    Ras signaling pathway PLCG2; FGFR2; PLA2G1B; ARF6; GNB2; PIK3CD; FGF9; GRIN2B; RAP1B; PIK3CB
    Rap signaling pathway ITGAL; PIK3R2; PDGFRB; TEK; Pdgfa&Pdgfb; INS; PRKD1; ITGB1; Fgf15; RAC2
    PIK-Akt signaling pathway GNB4; IFNAR1; ATF4; LAMB1; FGF5; PPP2R5D; GNGT2; LAMA5; EPOR; THBS1
    Regulation of actin cytoskeleton SCINLA; SCIN; PIP5K2; FGF18; MAP2K2A; ITGAM; RAC3A; PIP5KL1; RAF1A; TMSB4Y
    Pathways in cancer TRAF1; VHL; GNAQ; PRKCG; PTCH2; FN1; BRAF; RAC2; MMP9; AXIN2
    Melanoma PIK3CD; KRAS; PIK3CG; FGF12; FGF11; HRAS; PIK3R1; BAD; CDH1; PIK3CA

    FGF6 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF6 itself. We selected most functions FGF6 had, and list some proteins which have the same functions with FGF6. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor binding FGF22; FGF16; FGF2; Fgf15; FGF10; FGF20B; FRS3; FGF6B; FGF20A; FGF9
    growth factor activity JAG1; TGFB2; COL20A1; ANGPTL3; CDNF; WISP3; FGF10; NENF; FGF12B; GDF15

    FGF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF6.

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