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FZD3

  • Official Full Name

    frizzled family receptor 3

  • Overview

    This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.
  • Synonyms

    FZD3; frizzled family receptor 3; frizzled (Drosophila) homolog 3 , frizzled 3, seven transmembrane spanning receptor , frizzled homolog 3 (Drosophila); frizzled-3; frizzled homolog 3; frizzled 3, seven transmembrane spanning receptor; Fz-3;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FZD3-13066H Recombinant Human FZD3, GST-tagged E.coli GST 23-188a.a.
Human FZD3-12H Recombinant Human FZD3 Protein, GST-tagged Wheat Germ GST 55 a.a. - 157 a.a.
Human FZD3-6207H Recombinant Human FZD3 Protein, GST-tagged Wheat Germ GST
Human FZD3-1082HF Recombinant Full Length Human FZD3 Protein, GST-tagged In Vitro Cell Free System GST 55-157 amino acids
Human FZD3-0294H Recombinant Human FZD3 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 23-666aa
Mouse FZD3-6117M Recombinant Mouse FZD3 Protein Mammalian Cell His
Mouse FZD3-3409M Recombinant Mouse FZD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FZD3-3409M-B Recombinant Mouse FZD3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL16362HF Recombinant Full Length Human Frizzled-3(Fzd3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-666)
Mus musculus (Mouse) RFL2541MF Recombinant Full Length Mouse Frizzled-3(Fzd3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-666)
Rhesus Macaque FZD3-1775R Recombinant Rhesus monkey FZD3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FZD3-1596R Recombinant Rhesus Macaque FZD3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque FZD3-1596R-B Recombinant Rhesus Macaque FZD3 Protein Pre-coupled Magnetic Beads HEK293
Xenopus laevis (African clawed frog) RFL19095XF Recombinant Full Length Xenopus Laevis Frizzled-3(Fzd3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (17-664)
Chicken FZD3-4687C Recombinant Chicken FZD3 Mammalian Cell His
Chicken FZD3-4686C Recombinant Chicken FZD3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FZD3 Related Signal Pathway

FZD3 involved in several pathways and played different roles in them. We selected most pathways FZD3 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with FZD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayRAC1;MMP7;WNT4;CER1;DKK1B;TBL1Y;RAC3A;FZD3B;BAMBIB
Hippo signaling pathwayTCF7;WNT9B;TEAD4;JUB;FRMD6;CRB2;FZD9;NF2;WTIP
Signaling pathways regulating pluripotency of stem cellsPIK3CD;IL6ST;FZD6;KRAS;DLX5;AXIN2;WNT8A;PAX6;PIK3CG
MelanogenesisWNT4;PRKCA;TYRP1B;WNT2BB;WNT2BA;DVL3A;WNT5A;ASIP;CALM3B
HTLV-I infectionNRAS;PPP3CC;WNT8A;RAN;PIK3CA;GPS2;ANAPC11;SMAD2;APC
Pathways in cancerTGFB1;WNT16;FGFR1;STAT1;PDGFRB;Shh;PDGFB;LAMA5;Ar
Proteoglycans in cancerRPS6KB2;FZD5;CAMK2B;HSPB2;CAV3;EZR;PLCE1;SRC;AKT1
MicroRNAs in cancerITGA5;RAF1;ZEB2;ZFPM2;UBE2I;CD44;HOXD10;PTEN;EZR
Basal cell carcinomaFZD1;WNT2;WNT3;GLI3;WNT4;PTCH2;GSK3B;SMO;WNT9A

FZD3 has several biochemical functions, for example, G-protein coupled receptor activity, PDZ domain binding, Wnt-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FZD3 itself. We selected most functions FZD3 had, and list some proteins which have the same functions with FZD3. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityMTNR1BA;GPR157;PROKR1;CXCR4A;SETD6;FZD6;TAS2R134;GPR146;TAS2R202
PDZ domain bindingCCDC88C;LPAR2;LRP2;SLC9A3R1;PTENA;KIF14;GRID2;GRIK2;DLC
Wnt-activated receptor activityLRP2A;FZD5;FZD2;Fzd4;LRP5;FZD7B;FZD3A;FZD8;FZD1
Wnt-protein bindingFZD3B;FZD7B;LRP6;LRP5L;PORCN;SETD6;FZD3A;FZD6;EVLA
protein bindingFLT3;RTN4;PLAU;SIAH2;NUDC;FAM69A;TACR1;ZNF502;NR5A2

FZD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FZD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FZD3.

SDCBP

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