GALNT2
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Official Full Name
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
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Overview
This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases. -
Synonyms
GALNT2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); polypeptide N-acetylgalactosaminyltransferase 2; GalNAc T2; GalNAc-T2; GALT2_HUMAN; GaNTase 2; Polypeptide GalNAc transferase 2; Polypeptide N acetylgalactosaminyltransferase 2 soluble form; Polypeptide N-acetylgalactosaminyltransferase 2 soluble form; pp GaNTase 2; pp-GaNTase 2; Protein UDP acetylgalactosaminyltransferase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP GalNAc transferase 2; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc transferase 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Rhizobia
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human Cell
- Mammalian Cell
- P. pastoris
- Wheat Germ
- Fc
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GALNT2 Related Articles
GALNT2 involved in several pathways and played different roles in them. We selected most pathways GALNT2 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Mucin type O-Glycan biosynthesis | B3GNT6;C1GALT1C1;C1GALT1;ST3GAL1;GALNT14;GALNT13;GALNT4;POC1BL;GCNT4 |
Metabolic pathways | GBA;ETNK2;CYP2C19;GANAB;MDH1AA;TM7SF2;DHRS3B;COQ7;MGAT5 |
GALNT2 has several biochemical functions, for example, carbohydrate binding, manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT2 itself. We selected most functions GALNT2 had, and list some proteins which have the same functions with GALNT2. You can find most of the proteins on our site.
Function | Related Protein |
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carbohydrate binding | ILLR3;CNTN2;LGALS9L1;LMAN1L;SIGLEC11;CANX;GALNT7;LGALS2;CLEC4A |
manganese ion binding | ATP2C1;DYRK2;ARG1;IMPA1;SLC11A2;PPM1NB;PPM1AA;PPM1BB;CDIPT |
polypeptide N-acetylgalactosaminyltransferase activity | GALNT4;GALNT11;GALNT12;GALNT7;GALNT3;GALNT14;GALNTL2;GALNTL1;GALNT10 |
protein binding | ARHGEF4;TROAP;EHD3;TTN;TECPR2;SPATA2;PIGS;HIST1H4E;MARVELD2 |
GALNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT2.
CCDC155; NOD2; AP4M1; Shoc2; Itgb1; PTPN1; Rab5c; Rad54l; REEP5; Papss1; MMGT1; Tor1aip1; Hspa14; Mis12; AP4S1; Uso1
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