galnt2
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  • Official Full Name
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
  • Background
  • This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.
  • Synonyms
  • GALNT2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); polypeptide N-acetylgalactosaminyltransferase 2; GalNAc T2; GalNAc-T2; GALT2_HUMAN; GaNTase 2; Polypeptide GalNAc transferase 2; Polypeptide N acetylgalactosaminyltransferase 2 soluble form; Polypeptide N-acetylgalactosaminyltransferase 2 soluble form; pp GaNTase 2; pp-GaNTase 2; Protein UDP acetylgalactosaminyltransferase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP GalNAc transferase 2; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc transferase 2
Cat.#:GALNT2-1252HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GALNT2 Protein, MYC/DDK-tagged
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Cat.#:GALNT2-4698HTag:
Source (Host):P. pastorisSpecies:Human
Product nameRecombinant Human GALNT2 Protein
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Cat.#:GALNT2-4699HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GALNT2 Protein, GST-tagged
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Cat.#:GALNT2-4700RTag:
Source (Host):E. coliSpecies:Rhizobia
Product nameRecombinant Rhizobia GALNT2 Protein
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Cat.#:GALNT2-13136HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GALNT2, His-tagged
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Cat.#:GALNT2-229HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human GALNT2, His tagged
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Cat.#:GALNT2-27303THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GALNT2
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Cat.#:GALNT2-585HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GALNT2
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Cat.#:GALNT2-6185MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GALNT2 Protein
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Cat.#:GALNT2-1807RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GALNT2 Protein, His-tagged
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Cat.#:GALNT2-6862ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GALNT2
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Cat.#:GALNT2-907HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human GALNT2 cell lysate
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Involved Pathway

GALNT2 involved in several pathways and played different roles in them. We selected most pathways GALNT2 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Mucin type O-Glycan biosynthesis
GALNTL5; POC1BL; GALNT10; GALNT7; GCNT4A; B4GALT5; C1GALT1A; GCNT4; GALNT5; GALNTL1
Metabolic pathways
UQCRQ; CKMT1B; GALNT3; AOX1; BCKDHA; CMPK; GBA2; PISD; PI4KAA; MOCS1

Protein Function

GALNT2 has several biochemical functions, for example, carbohydrate binding, manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT2 itself. We selected most functions GALNT2 had, and list some proteins which have the same functions with GALNT2. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein GFPT1; MAN2B2; KLRC2; PRPS2; CLEC2G; LGALS9C; KLRB1F; GALNT9; CLC; KLRC1
Function manganese ion binding
Related Protein FAM20C; NUDT7; LARGE; GYLTL1B; MRE11A; DYRK2; WRN; GLUL; LAP3; PIM1
Function polypeptide N-acetylgalactosaminyltransferase activity
Related Protein GALNTL2; GALNT1; GALNT5; GALNT4; GALNTL4; GALNT6; WBSCR17; GALNT10; GALNT14; GALNT9
Function protein binding
Related Protein HNRNPH3; TMEM43; CFL1; GPX3; SNX8; NMB; RTN4RL1B; SRPK2; TRP53; UPP2

Interacting Protein

GALNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT2.
CCDC155; NOD2; AP4M1; Shoc2; Itgb1; PTPN1; Rab5c; Rad54l; REEP5; Papss1; MMGT1; Tor1aip1; Hspa14; Mis12; AP4S1; Uso1

GALNT2 Related Articles

Ho, WL; Chou, CH; et al. GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma. ONCOTARGET 5:12247-12259(2014).
Cole, CB; Nikpay, M; et al. Adiposity significantly modifies genetic risk for dyslipidemia. JOURNAL OF LIPID RESEARCH 55:2416-2422(2014).