GATAD2A
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Official Full Name
GATA zinc finger domain containing 2A
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Synonyms
GATAD2A; GATA zinc finger domain containing 2A; transcriptional repressor p66-alpha; p66 alpha; p66alpha; hp66alpha; GATA zinc finger domain-containing protein 2A; FLJ20085; FLJ21017;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | GATAD2A-13169H | Recombinant Human GATAD2A, His-tagged | E.coli | His | C-term-266a.a. | |
Human | GATAD2A-4756H | Recombinant Human GATAD2A Protein, GST-tagged | Wheat Germ | GST | ||
Human | GATAD2A-5473HF | Recombinant Full Length Human GATAD2A Protein, GST-tagged | In Vitro Cell Free System | GST | 566 amino acids | |
Chicken | GATAD2A-1925C | Recombinant Chicken GATAD2A | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
GATAD2A involved in several pathways and played different roles in them. We selected most pathways GATAD2A participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATAD2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Chromatin modifying enzymes | SMARCD3;VPS72;EP400;ENY2;ANO9A;CSRP2BP;KDM4D;PBRM1L;ING3 |
Chromatin organization | DMAP1;BRPF3;COPRS;TAF6L;KDM4D;KDM5C;MSL3;PRMT7;BRPF1 |
Gene Expression | ESR2A;DNMT1;UHRF1;RBM5;BCAS2;MED6;ZKSCAN5;NR1I3;NFIC |
HDACs deacetylate histones | BRMS1;CHD4;MTA1;MTA2;MTA3;KDM1A;GATAD2B;SAP30L;GATAD2AB |
RNA Polymerase I Promoter Clearance | UBTF;GATAD2A;MTA1;MTA3;TAF1D;CHD4A;EHMT2;TAF1C;MBD3 |
RNA Polymerase I Transcription | CHD4;TAF1A;TAF1B;MTA1;PTRF;GATAD2A;MBD3B;CD3EAP;TAF1C |
RNA Polymerase I Transcription Initiation | GATAD2AB;RRN3;MBD3B;MBD3A;MTA2;GATAD2A;UBTF;MTA1;CHD4 |
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | BRF1;CHD4A;SNAPC1;MTERF;GTF3AA;POU2F1B;CRCP;GTF3C3;CHD4 |
GATAD2A has several biochemical functions, for example, contributes_to RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by GATAD2A itself. We selected most functions GATAD2A had, and list some proteins which have the same functions with GATAD2A. You can find most of the proteins on our site.
Function | Related Protein |
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contributes_to RNA polymerase II regulatory region sequence-specific DNA binding | GATAD2AB;GATAD2A |
protein binding | SMAP2;CNTF;VASH1;HSD17B10;XK;YWHAQ;SMAD2;S100A14;RPLP0 |
protein binding, bridging | TRIM5;TRIM22;FLRT1;SH2D1B;CUX1;TRIM17;CNTLN;TRIM6;TJP2 |
transcription factor activity, sequence-specific DNA binding | E2F6;MAFBB;HIRA;HOXA3A;SOX2;ZSCAN2;ZSCAN4C;RCAN1;GPBP1 |
zinc ion binding | ZDHHC20;DTX2;MICAL2B;ZNF385B;ZDHHC16;PDXK;LHX8A;ACE;ADAM20 |
GATAD2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATAD2A here. Most of them are supplied by our site. Hope this information will be useful for your research of GATAD2A.
HDAC1; CDK2AP1; HDAC2; His2B:CG33868; His3:CG33857; His4:CG33869; His2A:CG33808; KAT2B; MBD2; PAK4; q99ib8-pro_0000045599; Cdk2ap1; PTBP3; MBD3; KRAS; Junb
- Q&As
- Reviews
Q&As (6)
Ask a questionCell models and animal models can be used to study the function of GATAD2A. For example, gene knockout or overexpression techniques can be used to regulate the expression of GATAD2A and observe its impact on biological processes such as cell proliferation, differentiation, and apoptosis.
GATAD2A interactions with other molecules can affect the activity and stability of its transcription factors, thereby regulating the expression of its downstream genes. Studying these interactions can help uncover the complex regulatory mechanisms of GATAD2A in biological processes.
Studies have shown that the aberrant expression of GATAD2A is associated with the occurrence of a variety of diseases, such as cancer, neurological diseases, and developmental disorders. Mutations or overexpression of GATAD2A may be closely related to the onset and progression of these diseases.
Certain biomolecules can serve as molecular markers for GATAD2A, such as mRNA or proteins of GATAD2A detected in biological samples such as blood, urine, etc. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
Treatment strategies for GATAD2A include inhibiting their expression, modulating their activity, or using gene therapy, among other things. For example, the development of small molecule inhibitors or antibody drugs against GATAD2A to inhibit their aberrant activity in disease.
The role of GATAD2A in disease can be assessed through in-depth analysis of the patient's genomic data and combined with the results of studies in cell and animal models. This can help doctors better understand the patient's condition and develop more effective treatment plans.
Customer Reviews (3)
Write a reviewIt is effective in experiments and has strong stability.
It is widely used and suitable for all kinds of biological experiments.
The cost is moderate, the performance is good, and it is more cost-effective for experiments.
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