Recombinant Human GATAD2A Protein, GST-tagged
Cat.No. : | GATAD2A-4756H |
Product Overview : | Human GATAD2A full-length ORF (1 a.a. - 566 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | GATAD2A (GATA Zinc Finger Domain Containing 2A) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Development NOTCH1-mediated pathway for NF-KB activity modulation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein binding, bridging. An important paralog of this gene is GATAD2B. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 88.66 kDa |
AA Sequence : | MAMGRGEGLVGDGPVDMRTSHSDMK SERRPPSPDVIVLSDNEQPSSPRVN GLTTVALKETSTEALMKSSPEERER MIKQLKEELRLEEAKLVLLKKLRQS QIQKEATAQKPTGSVGSTVTTPPPL VRGTQNIPAGKPSLQTSSARMPGSV IPPPLVRGGQQASSKLGPQASSQVV MPPLVRGAQQIHSIRQHSSTGPPPL LLAPRASVPSVQIQGQRIIQQGLIR VANVPNTSLLVNIPQPTPASLKGTT ATSAQANSTPTSVASVVTSAESPAS RQAAAKLALRKQLEKTLLEIPPPKP PAPEMNFLPSAANNEFIYLVGLEEV VQNLLETQAGRMSAATVLSREPYMC AQCKTDFTCRWREEKSGAIMCENCM TTNQKKALKVEHTSRLKAAFVKALQ QEQEIEQRLLQQGTAPAQAKAEPTA APHPVLKQVIKPRRKLAFRSGEARD WSNGAVLQASSQLSRGSATTPRGVL HTFSPSPKLQNSASATALVSRTGRH SERTVSAGKGSATSNWKKTPLSTGG TLAFVSPSLAVHKSSSAVDRQREYL LDMIPPRSIPQSATWK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GATAD2A GATA zinc finger domain containing 2A [ Homo sapiens ] |
Official Symbol : | GATAD2A |
Synonyms : | GATAD2A; GATA zinc finger domain containing 2A; transcriptional repressor p66-alpha; p66 alpha; p66alpha; hp66alpha; GATA zinc finger domain-containing protein 2A; FLJ20085; FLJ21017; |
Gene ID : | 54815 |
mRNA Refseq : | NM_017660 |
Protein Refseq : | NP_060130 |
MIM : | 614997 |
UniProt ID : | Q86YP4 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionCell models and animal models can be used to study the function of GATAD2A. For example, gene knockout or overexpression techniques can be used to regulate the expression of GATAD2A and observe its impact on biological processes such as cell proliferation, differentiation, and apoptosis.
GATAD2A interactions with other molecules can affect the activity and stability of its transcription factors, thereby regulating the expression of its downstream genes. Studying these interactions can help uncover the complex regulatory mechanisms of GATAD2A in biological processes.
Studies have shown that the aberrant expression of GATAD2A is associated with the occurrence of a variety of diseases, such as cancer, neurological diseases, and developmental disorders. Mutations or overexpression of GATAD2A may be closely related to the onset and progression of these diseases.
Certain biomolecules can serve as molecular markers for GATAD2A, such as mRNA or proteins of GATAD2A detected in biological samples such as blood, urine, etc. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
Treatment strategies for GATAD2A include inhibiting their expression, modulating their activity, or using gene therapy, among other things. For example, the development of small molecule inhibitors or antibody drugs against GATAD2A to inhibit their aberrant activity in disease.
The role of GATAD2A in disease can be assessed through in-depth analysis of the patient's genomic data and combined with the results of studies in cell and animal models. This can help doctors better understand the patient's condition and develop more effective treatment plans.
Customer Reviews (3)
Write a reviewIt is effective in experiments and has strong stability.
It is widely used and suitable for all kinds of biological experiments.
The cost is moderate, the performance is good, and it is more cost-effective for experiments.
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