gdf1
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  • Official Full Name
  • growth differentiation factor 1
  • Background
  • This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of;proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein;containing seven conserved cysteine residues. The members of this family are regulators of cell growth and;differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the;establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This;protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene.
  • Synonyms
  • GDF1; growth differentiation factor 1; embryonic growth/differentiation factor 1; GDF-1; DORV; DTGA3
Cat.#:GDF1-4817HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDF1 Protein, GST-tagged
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Cat.#:Gdf1-269MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdf1 Protein, His-tagged
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Cat.#:Gdf1-270RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdf1 Protein, His-tagged
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Cat.#:GDF1-715HTag:
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human GDF1
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Cat.#:GDF1-717HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Growth Differentiation Factor 1
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Involved Pathway

GDF1 involved in several pathways and played different roles in them. We selected most pathways GDF1 participated on our site, such as Developmental Biology, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Developmental Biology
KCNQ2; DPYSL2B; EFNA1B; ACTR3; HFE2; CNTN6; EFNA3B; DUSP4; DUSP1; CDK5R1B
Metabolism
ARL2BP; LYVE1; TCN1; CYP2D6; LRPPRC; CYP4F22; NHLRC1; Agmo; NUDT4B; NUBP2
Metabolism of lipids and lipoproteins
CYP11B1; SLC44A5B; SGMS2; PLBD1; CYP2U1; CHKA; APOC2; THEM5; SACM1L; CERS5
Signaling by NODAL
FOXH1; TDGF1; GDF1; LEFTY1; DRAP1; CFC1; ACVR1C; PCSK6
Sphingolipid de novo biosynthesis
VAPB; GDF1; PPM1LA; SGMS2; COL4A3BP; CERS5; CERS3B; CERS4A; PPM1LB; ACER1
Sphingolipid metabolism
SPTLC2; SGPP1; NEU3.1; ASAH1A; PPAP2D; SMPD2A; SERINC1; CERS1; SGMS2; NEU3.4

Protein Function

GDF1 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF1 itself. We selected most functions GDF1 had, and list some proteins which have the same functions with GDF1. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein IFNT2; MSTNA; GDF2; IL33; IL17F; GDF3; BMP8A; IL6; GDF10; GDF5
Function growth factor activity
Related Protein FGF14; ANGPTL3; FGF18B; TIMP1; EPGN; VEGFA; EGF; BMP2B; GDF11; FGF20
Function transforming growth factor beta receptor binding
Related Protein NDR2; GDF11; NDR1; BMP8B; GDF10; BMP10; GDF9; BMP8A; SPAW; INHA

GDF1 Related Gene Family

TGF