|Official Full Name||growth differentiation factor 1|
|Background||This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of;proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein;containing seven conserved cysteine residues. The members of this family are regulators of cell growth and;differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the;establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This;protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene.|
|Synonyms||GDF1; growth differentiation factor 1; embryonic growth/differentiation factor 1; GDF-1; DORV; DTGA3|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GDF1 involved in several pathways and played different roles in them. We selected most pathways GDF1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Developmental Biology||HFE2; MED22; DNM2; AP2S1; CDK8; TDGF1; RASGRP4; SEMA3AA; MED21; POU5F3|
|Metabolism||Alb; SREBF2; NOSIP; C20orf7; AWAT2; LSM1; OAZ2B; PLBD1; CYP2K16; KCNG4|
|Metabolism of lipids and lipoproteins||MED9; MED18; SLC25A1A; ACER1; INSIG1; FAAH2; FAAH2A; CSNK1G2; CHKB; OSBP|
|Signaling by NODAL||TDGF1; CFC1; GDF1; FOXH1; ACVR1C; DRAP1; LEFTY1; PCSK6|
|Sphingolipid de novo biosynthesis||COL4A3BP; GDF1; CERS3B; VAPB; OSBP; PPM1LA; FA2H; PPM1LB; SPTLC1; CERS4A|
|Sphingolipid metabolism||SGPP2; NEU2; NEU3.3; NEU3.5; SPHK1; CERK; KDSR; ENPP7; PPAP2D; ARSH|
GDF1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF1 itself. We selected most functions GDF1 had, and list some proteins which have the same functions with GDF1. You can find most of the proteins on our site.
|cytokine activity||FAM3B; LEFTY2; INHBE; TXLNA; GREM1; IL17A; IFNA4; IL17A/F1; CSF1; BMP10|
|growth factor activity||CDNF; IL34; VHL; NUDT6; CSF1A; NDP; PDGFAB; INHA; PPBP; KLK1B3|
|transforming growth factor beta receptor binding||GDF15; MSTNA; GDF11; BMP4; FKBP1A; INHBAA; SMAD3; MSTN; BMP8A; LRG1|
GDF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF1.