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Official Full Name geranylgeranyl diphosphate synthase 1
Background This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.
Synonyms GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; GGPPS1; GGPPSase; GGPP synthase; geranyltranstransferase; farnesyltranstransferase; dimethylallyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosp
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GGPS1-13243H Recombinant Human GGPS1, GST-tagged E.coli GST
    Human GGPS1-2800H Recombinant Human Geranylgeranyl Diphosphate Synthase 1, His-tagged E.coli His
    Human GGPS1-29020TH Recombinant Human GGPS1, His-tagged E.coli His
    Human GGPS1-4873H Recombinant Human GGPS1 Protein, GST-tagged Wheat Germ GST
    Human GGPS1-5946HCL Recombinant Human GGPS1 293 Cell Lysate HEK293 N/A
    Human GGPS1-677H Recombinant Human GGPS1 Protein, His-tagged HEK293 His
    Human GGPS1-825H Recombinant Human Geranylgeranyl Diphosphate Synthase 1, T7-tagged E.coli T7
    Mouse Ggps1-7828M Recombinant Mouse Ggps1 protein, His & T7-tagged E.coli His/T7
    Rat GGPS1-2522R Recombinant Rat GGPS1 Protein Mammalian Cell His
    Rhesus Macaque GGPS1-1840R Recombinant Rhesus monkey GGPS1 Protein, His-tagged Mammalian Cell His
    Zebrafish GGPS1-8448Z Recombinant Zebrafish GGPS1 Mammalian Cell His

    GGPS1 involved in several pathways and played different roles in them. We selected most pathways GGPS1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGPS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Terpenoid backbone biosynthesis PMVK; PDSS1; DHDDS; HMGCS1; GGPS1; NUS1; MVD; ACAT1; HMGCRB; HMGCRA
    Metabolic pathways POLA1; ALG2; FPGT; PKM; OGDHA; TAT; PKM2; MTMR1B; KDSR; DAO.2

    GGPS1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GGPS1 itself. We selected most functions GGPS1 had, and list some proteins which have the same functions with GGPS1. You can find most of the proteins on our site.

    Function Related Protein
    dimethylallyltranstransferase activity GGPS1; FDPS
    farnesyltranstransferase activity GGPS1; FNTB; COX10
    geranyltranstransferase activity GGPS1; FDPS
    metal ion binding PC; DMRTA1; HMOX2; ZFP354C; ZFP42; ZYMND12; COX4I2; RNF34A; FTR54; ZNF766
    protein binding NAP1L4; ZMAT4; HSPBAP1; RTN4A; MCM4; CCDC24; ARID5A; MAPK8; TBX6; SP4

    GGPS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGPS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGPS1.


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