ggps1
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  • Official Full Name
  • geranylgeranyl diphosphate synthase 1
  • Background
  • This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.
  • Synonyms
  • GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; GGPPS1; GGPPSase; GGPP synthase; geranyltranstransferase; farnesyltranstransferase; dimethylallyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosp
Cat.#:GGPS1-4873HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GGPS1 Protein, GST-tagged
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Cat.#:GGPS1-13243HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGPS1, GST-tagged
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Cat.#:GGPS1-2800HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Geranylgeranyl Diphosphate Synthase 1, His-tagged
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Cat.#:GGPS1-29020THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGPS1, His-tagged
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Cat.#:GGPS1-677HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human GGPS1 Protein, His-tagged
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Cat.#:GGPS1-825HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Geranylgeranyl Diphosphate Synthase 1, T7-tagged
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Cat.#:Ggps1-7828MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ggps1 protein, His & T7-tagged
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Cat.#:GGPS1-2522RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GGPS1 Protein
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Cat.#:GGPS1-1840RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GGPS1 Protein, His-tagged
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Cat.#:GGPS1-8448ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GGPS1
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Cat.#:GGPS1-5946HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GGPS1 293 Cell Lysate
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Involved Pathway

GGPS1 involved in several pathways and played different roles in them. We selected most pathways GGPS1 participated on our site, such as Terpenoid backbone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGPS1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Terpenoid backbone biosynthesis
HMGCR; ACAT2; PDSS1; FNTA; DHDDS; HMGCS1; PDSS2; MVD; ZMPSTE24; HMGCS2
Metabolic pathways
IMPA2; PET112L; FBP1A; PTGES3A; PLD3; BCMO1; AOX1; POLR2C; SORD; B3GALT5

Protein Function

GGPS1 has several biochemical functions, for example, dimethylallyltranstransferase activity, farnesyltranstransferase activity, geranyltranstransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGPS1 itself. We selected most functions GGPS1 had, and list some proteins which have the same functions with GGPS1. You can find most of the proteins on our site.
Function
Related Protein
Function dimethylallyltranstransferase activity
Related Protein GGPS1; FDPS
Function farnesyltranstransferase activity
Related Protein GGPS1; COX10; FNTB
Function geranyltranstransferase activity
Related Protein FDPS; GGPS1
Function metal ion binding
Related Protein GMEB2; ADPGK; SEMG1; XPNPEP2; SLC25A25A; PLAGX; ZNF330; ZBTB7B; MTBL; ZFP787
Function protein binding
Related Protein PELI3; PIN4; HUWE1; SAP30; CTLA2B; PTPN12; SERP2; HACE1; SFRP4; FAM131B

Interacting Protein

GGPS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGPS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGPS1.
ATOX1